Epigenetics & Nuclear Signaling Antibodies 3
Anti-IRF2BP1 Antibody (CAB4614)
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- SKU:
- CAB4614
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IRF2BP1
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | IRF2BP1 Rabbit pAb |
| Product Code: | CAB4614 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | IRF2BP1 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-87MG, HeLa, Jurkat, Mouse eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VLPE GRSP GPPA LKHP ATKD LAAA AAQG PQLP PPQA QPQP SGTG GGVS GQDR YDRA TSSG RLPL PSPA LEYT LGSR LANG LGRE EAVA EGAR RALL GSMP GLMP PGLL AAAV SGLG SRGL TLAP GLSP ARPL FGSD FEKE KQQR NADC LAEL NEAM RGRA EEWH GRPK AVRE QLLA LSAC A |
| Gene ID: | 26145 |
| Uniprot: | Q8IU81 |
| Cellular Location: | Nucleus |
| Calculated MW: | 61kDa |
| Observed MW: | 62kDa |
| UniProt Protein Function: | IRF2BP1: Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. Belongs to the IRF2BP family. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; EC 6.3.2.- Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: nucleoplasm; intracellular membrane-bound organelle Molecular Function:protein binding; metal ion binding; ligase activity Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Code: | Q8IU81 |
| NCBI GenInfo Identifier: | 74727955 |
| NCBI Gene ID: | 26145 |
| NCBI Accession: | Q8IU81.1 |
| UniProt Secondary Accession: | Q8IU81,Q53EL7, Q6DC95, Q9BRZ9, Q9Y4P4, |
| UniProt Related Accession: | Q8IU81 |
| Molecular Weight: | 584 |
| NCBI Full Name: | Interferon regulatory factor 2-binding protein 1 |
| NCBI Synonym Full Names: | interferon regulatory factor 2 binding protein 1 |
| NCBI Official Symbol: | IRF2BP1 |
| NCBI Protein Information: | interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; probable E3 ubiquitin-protein ligase IRF2BP1 |
| UniProt Protein Name: | Interferon regulatory factor 2-binding protein 1 |
| UniProt Synonym Protein Names: | Probable E3 ubiquitin-protein ligase IRF2BP1 (EC:6.3.2.-) |
| Protein Family: | Interferon regulatory factor 2-binding protein |
| UniProt Gene Name: | IRF2BP1 |
| UniProt Entry Name: | I2BP1_HUMAN |
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