Name: Anti-IP6K2 Antibody (CAB7192)
Brand: Metabolism Antibodies 2
SKU: CAB7192
Availability: OutOfStock

Antibody Name:	Anti-IP6K2 Antibody
Antibody SKU:	CAB7192
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human IP6K2 (NP_057375.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human
Positive Samples:	Raji, MCF7

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human IP6K2 (NP_057375.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MSPA FRAM DVEP RAKG VLLE PFVH QVGG HSCV LRFN ETTL CKPL VPRE HQFY ETLP AEMR KFTP QYKG VVSV RFEE DEDR NLCL IAYP LKGD HGIV DIVD NSDC EPKS KLLR WTTN KKHH VLET EKTP KDWV RQHR KEEK MKSH KLEE EFEW LKKS EVLY YTVE KKGN ISSQ LKHY NPWS
Gene ID:	51447
Uniprot:	Q9UHH9
Cellular Location:	Nucleus
Calculated MW:	8kDa/9kDa/11kDa/20kDa/21kDa/49kDa
Observed MW:	49kDa

Synonyms:

IP6K2, IHPK2, PIUS

Background:

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt Protein Function:	IHPK2: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Kinase, other; Motility/polarity/chemotaxis; EC 2.7.4.21 Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: intermediate filament cytoskeleton; nucleoplasm; nucleus Molecular Function:inositol 1,3,4,5,6-pentakisphosphate kinase activity; inositol heptakisphosphate kinase activity; inositol hexakisphosphate kinase activity; protein binding Biological Process: inositol phosphate metabolic process; negative regulation of cell growth; phosphoinositide phosphorylation; positive regulation of apoptosis
NCBI Summary:	This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9UHH9
NCBI GenInfo Identifier:	50400688
NCBI Gene ID:	51447
NCBI Accession:	Q9UHH9.2
UniProt Secondary Accession:	Q9UHH9,Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6 A8K3B1, B4E3G6, G8JLL6,
UniProt Related Accession:	Q9UHH9
Molecular Weight:	9,825 Da
NCBI Full Name:	Inositol hexakisphosphate kinase 2
NCBI Synonym Full Names:	inositol hexakisphosphate kinase 2
NCBI Official Symbol:	IP6K2
NCBI Official Synonym Symbols:	PIUS; IHPK2
NCBI Protein Information:	inositol hexakisphosphate kinase 2
UniProt Protein Name:	Inositol hexakisphosphate kinase 2
UniProt Synonym Protein Names:	P(i)-uptake stimulator; PiUS
Protein Family:	Inositol hexakisphosphate kinase
UniProt Gene Name:	IP6K2
UniProt Entry Name:	IP6K2_HUMAN

Western blot analysis of extracts of various cell lines, using IP6K2 antibody (CAB7192) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.

Antibodies

Anti-IP6K2 Antibody (CAB13427)

IP6K2 Antibody (PACO00977)

IP6K2 Antibody (PACO09980)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)