Cell Biology Antibodies 2
Anti-IP6K1 Antibody (CAB12216)
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- SKU:
- CAB12216
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-IP6K1 Antibody |
| Antibody SKU: | CAB12216 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IP6K1 (NP_695005.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, HepG2, Mouse brain, Rat brain, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IP6K1 (NP_695005.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MCVC QTME VGQY GKNA SRAG DRGV LLEP FIHQ VGGH SSMM RYDD HTVC KPLI SREQ RFYE SLPP EMKE FTPE YKGV VSVC FEGD SDGY INLV AYPY VESE TVEQ DDTT EREQ PRRK HSRR SLHR SGSG SDHK EEKA SLSL ETSE SSQE AKSP KVEL HSHS EVPF QMLD GNSG LSSE KISH NPWS LRCH KQQL SRMR SESK DRKL YKFL LLEN VVHH FKYP |
| Gene ID: | 9807 |
| Uniprot: | Q92551 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 31kDa/50kDa |
| Observed MW: | 57kDa |
| Synonyms: | IP6K1, IHPK1, PiUS |
| Background: | This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | IHPK1: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 2.7.4.21; Kinase, other Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: cytosol; nucleolus; nucleoplasm; nucleus Molecular Function:inositol 1,3,4,5,6-pentakisphosphate kinase activity; inositol heptakisphosphate kinase activity; inositol hexakisphosphate kinase activity Biological Process: inositol phosphate metabolic process; phosphoinositide phosphorylation |
| NCBI Summary: | This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011] |
| UniProt Code: | Q92551 |
| NCBI GenInfo Identifier: | 50400597 |
| NCBI Gene ID: | 9807 |
| NCBI Accession: | Q92551.3 |
| UniProt Secondary Accession: | Q92551,Q7L3I7, Q96E38, A8K157, A8MUX4, |
| UniProt Related Accession: | Q92551 |
| Molecular Weight: | 31,524 Da |
| NCBI Full Name: | Inositol hexakisphosphate kinase 1 |
| NCBI Synonym Full Names: | inositol hexakisphosphate kinase 1 |
| NCBI Official Symbol: | IP6K1 |
| NCBI Official Synonym Symbols: | PiUS; IHPK1 |
| NCBI Protein Information: | inositol hexakisphosphate kinase 1 |
| UniProt Protein Name: | Inositol hexakisphosphate kinase 1 |
| UniProt Synonym Protein Names: | Inositol hexaphosphate kinase 1 |
| Protein Family: | Inositol hexakisphosphate kinase |
| UniProt Gene Name: | IP6K1 |
| UniProt Entry Name: | IP6K1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IP6K1 antibody (CAB12216) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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