Cell Biology Antibodies 16
Anti-Insulin receptor Antibody (CABP0043)
- SKU:
- CABP0043
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-Insulin receptor Antibody |
Antibody SKU: | CABP0043 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y1146 of human INSR and Y1131 of human IGF1R |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y1146 of human INSR and Y1131 of human IGF1R |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 3480/3643 |
Uniprot: | P08069/P06213 |
Cellular Location: | |
Calculated MW: | 154kDa/155kDa/156kDa |
Observed MW: | Refer to Figures |
Synonyms: | IGF1R/INSR |
Background: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |