Cell Biology Antibodies 1
Anti-INPP1 Antibody (CAB10372)
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- SKU:
- CAB10372
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-INPP1 Antibody |
| Antibody SKU: | CAB10372 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human INPP1 (NP_002185.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, HT-29, U-251MG, HeLa, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human INPP1 (NP_002185.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSDI LREL LCVS EKAA NIAR ACRQ QEAL FQLL IEEK KEGE KNKK FAVD FKTL ADVL VQEV IKQN MENK FPGL EKNI FGEE SNEF TNDW GEKI TLRL CSTE EETA ELLS KVLN GNKV ASEA LARV VHQD VAFT DPTL DSTE INVP QDIL GIWV DPID STYQ YIKG SADI KSNQ GIFP CGLQ |
| Gene ID: | 3628 |
| Uniprot: | P49441 |
| Cellular Location: | |
| Calculated MW: | 43kDa |
| Observed MW: | 44kDa |
| Synonyms: | INPP1 |
| Background: | This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1, 4-bisphosphate and inositol 1, 3, 4-trisphophosphate. |
| UniProt Protein Function: | INPP1: the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.57; Motility/polarity/chemotaxis; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 2q32.2 Cellular Component: cytosol Molecular Function:inositol-1,4-bisphosphate 1-phosphatase activity Biological Process: inositol phosphate metabolic process; phosphate metabolic process; signal transduction |
| NCBI Summary: | This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P49441 |
| NCBI GenInfo Identifier: | 1352464 |
| NCBI Gene ID: | 3628 |
| NCBI Accession: | P49441.1 |
| UniProt Related Accession: | P49441 |
| Molecular Weight: | 44kDa |
| NCBI Full Name: | Inositol polyphosphate 1-phosphatase |
| NCBI Synonym Full Names: | inositol polyphosphate-1-phosphatase |
| NCBI Official Symbol: | INPP1 |
| NCBI Protein Information: | inositol polyphosphate 1-phosphatase |
| UniProt Protein Name: | Inositol polyphosphate 1-phosphatase |
| Protein Family: | Inositol polyphosphate 1-phosphatase |
| UniProt Gene Name: | INPP1 |
 | Western blot analysis of extracts of various cell lines, using INPP1 antibody (CAB10372) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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