Cell Biology Antibodies 17
Anti-IMPACT Antibody (CAB18471)
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- SKU:
- CAB18471
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-IMPACT Antibody |
| Antibody SKU: | CAB18471 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human IMPACT. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human IMPACT. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55364 |
| Uniprot: | Q9P2X3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | RWDD5, IMPACT |
| Background: |
| UniProt Protein Function: | IMPACT: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. Belongs to the IMPACT family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 18q11.2-q12.1 Cellular Component: polysome Biological Process: cellular response to amino acid starvation; cellular response to glucose starvation; negative regulation of protein amino acid autophosphorylation; negative regulation of protein amino acid phosphorylation; negative regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation |
| UniProt Code: | Q9P2X3 |
| NCBI GenInfo Identifier: | 296434540 |
| NCBI Gene ID: | 55364 |
| NCBI Accession: | Q9P2X3.2 |
| UniProt Secondary Accession: | Q9P2X3,Q49AM0, Q9H2X4, A8MXG0, |
| UniProt Related Accession: | Q9P2X3 |
| Molecular Weight: | 22,999 Da |
| NCBI Full Name: | Protein IMPACT |
| NCBI Synonym Full Names: | impact RWD domain protein |
| NCBI Official Symbol: | IMPACT |
| NCBI Official Synonym Symbols: | RWDD5 |
| NCBI Protein Information: | protein IMPACT |
| UniProt Protein Name: | Protein IMPACT |
| UniProt Synonym Protein Names: | Imprinted and ancient gene protein homolog |
| Protein Family: | IMPACT family |
| UniProt Gene Name: | IMPACT |
| UniProt Entry Name: | IMPCT_HUMAN |
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