Metabolism Antibodies 3
Anti-IMP3 Antibody (CAB8855)
- SKU:
- CAB8855
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-IMP3 Antibody |
| Antibody SKU: | CAB8855 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human IMP3 (NP_060755.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SW620, Mouse liver, Mouse spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human IMP3 (NP_060755.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVRK LKFH EQKL LKQV DFLN WEVT DHNL HELR VLRR YRLQ RRED YTRY NQLS RAVR ELAR RLRD LPER DQFR VRAS AALL DKLY ALGL VPTR GSLE LCDF VTAS SFCR RRLP TVLL KLRM AQHL QAAV AFVE QGHV RVGP DVVT DPAF LVTR SMED FVTW VDSS KIKR HVLE YNEE RDDF DLEA |
| Gene ID: | 55272 |
| Uniprot: | Q9NV31 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 21kDa |
| Observed MW: | 22kDa |
| Synonyms: | IMP3, BRMS2, C15orf12, MRPS4 |
| Background: | This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. |
| UniProt Protein Function: | IMP3: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Belongs to the ribosomal protein S4P family.Protein type: Nucleolus; RNA processing; RNA-bindingChromosomal Location of Human Ortholog: 15q24Cellular Component: nucleolus; nucleoplasm; nucleus; small ribosomal subunit; small subunit processomeMolecular Function: protein binding; rRNA binding; snoRNA binding; structural constituent of ribosomeBiological Process: positive regulation of translational fidelity; rRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NV31 |
| NCBI GenInfo Identifier: | 52783099 |
| NCBI Gene ID: | 55272 |
| NCBI Accession: | Q9NV31.1 |
| UniProt Secondary Accession: | Q9NV31,Q53G10, B3KQ67 |
| UniProt Related Accession: | Q9NV31 |
| Molecular Weight: | 21,850 Da |
| NCBI Full Name: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| NCBI Synonym Full Names: | IMP3, U3 small nucleolar ribonucleoprotein |
| NCBI Official Symbol: | IMP3 |
| NCBI Official Synonym Symbols: | BRMS2; MRPS4; C15orf12 |
| NCBI Protein Information: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| UniProt Protein Name: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| UniProt Synonym Protein Names: | BRMS2 |
| Protein Family: | U3 small nucleolar ribonucleoprotein protein |
| UniProt Gene Name: | IMP3 |
| UniProt Entry Name: | IMP3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IMP3 antibody (CAB8855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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