Cell Biology Antibodies 4
Anti-ILKAP Antibody (CAB14305)
(No reviews yet)
Write a Review
- SKU:
- CAB14305
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ILKAP Antibody |
| Antibody SKU: | CAB14305 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-392 of human ILKAP (NP_110395.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, HepG2, Mouse spleen, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-392 of human ILKAP (NP_110395.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDLF GDLP EPER SPRP AAGK EAQK GPLL FDDL PPAS STDS GSGG PLLF DDLP PASS GDSG SLAT SISQ MVKT EGKG AKRK TSEE EKNG SEEL VEKK VCKA SSVI FGLK GYVA ERKG EREE MQDA HVIL NDIT EECR PPSS LITR VSYF AVFD GHGG IRAS KFAA QNLH QNLI RKFP KGDV ISVE KTVK RCLL DTFK HTDE EFLK QASS QKPA WKDG STAT CVLA VDNI LYIA NLGD SRAI LCRY NEES QKHA ALSL SKEH NPTQ YEER MRIQ KAGG NVRD GRVL GVLE VSRS IGDG QYKR CGVT SVPD IRRC QLTP NDRF ILLA CDGL FKVF TPEE AVNF ILSC LEDE KIQT REGK SAAD ARYE AACN RLAN KAVQ RGSA DNVT VMVV RIGH |
| Gene ID: | 80895 |
| Uniprot: | Q9H0C8 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |
| Synonyms: | ILKAP, ILKAP2, ILKAP3, PP2C-DELTA, PPM1O |
| Background: | The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. |
| UniProt Protein Function: | ILKAP: a protein serine/threonine phosphatase of the PP2C family. Can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| UniProt Protein Details: | Protein type:EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q37.3 Molecular Function:protein binding |
| NCBI Summary: | The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H0C8 |
| NCBI GenInfo Identifier: | 74752560 |
| NCBI Gene ID: | 80895 |
| NCBI Accession: | Q9H0C8.1 |
| UniProt Secondary Accession: | Q9H0C8,B3KM39, |
| UniProt Related Accession: | Q9H0C8 |
| Molecular Weight: | 42,907 Da |
| NCBI Full Name: | Integrin-linked kinase-associated serine/threonine phosphatase 2C |
| NCBI Synonym Full Names: | ILK associated serine/threonine phosphatase |
| NCBI Official Symbol: | ILKAP |
| NCBI Official Synonym Symbols: | PPM1O; ILKAP2; ILKAP3; PP2C-DELTA |
| NCBI Protein Information: | integrin-linked kinase-associated serine/threonine phosphatase 2C |
| UniProt Protein Name: | Integrin-linked kinase-associated serine/threonine phosphatase 2C |
| Protein Family: | Integrin-linked kinase-associated serine/threonine phosphatase |
| UniProt Gene Name: | ILKAP |
| UniProt Entry Name: | ILKAP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ILKAP Rabbit pAb (CAB14305) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
View AllClose
Related Products
Human ILKAP Recombinant Protein (RPES2073)
system_update_altDatasheetHuman ILKAP Recombinant Protein Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is cytoplasm protein which belongs to the
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक