Description
system_update_altDatasheet
SKU: | HDAB0208 |
Size: | 100 µg |
Clonality: | Monoclonal |
Clone: | DM218 |
Synonyms: | CD218a, CDw218a, IL-1Rrp, IL1RRP, IL18RA |
Applications: | ELISA, Flow Cyt |
Recommended Dilution: | ELISA 1:5000-10000; Flow Cyt 1:100 |
Host Species: | Rabbit |
Isotype: | Rabbit IgG |
Reactivity: | Human |
Purification Method: | Purified from cell culture supernatant by affinity chromatography |
Formulation: | Powder |
Buffer: | 1XPBS |
Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Usage: | Research use only |
Background: | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |