Cell Biology Antibodies 7
Anti-IL-9 Antibody (CAB1894)
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- SKU:
- CAB1894
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | IL9 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB1894 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human IL9 (NP_000581.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human IL9 (NP_000581.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QGCP TLAG ILDI NFLI NKMQ EDPA SKCH CSAN VTSC LCLG IPSD NCTR PCFS ERLS QMTN TTMQ TRYP LIFS RVKK SVEV LKNN KCPY FSCE QPCN QTTA GNAL TFLK SLLE IFQK EKMR GMRG KI |
| Gene ID: | 3578 |
| Uniprot: | P15248 |
| Cellular Location: | Secreted |
| Calculated MW: | 15kDa |
| Observed MW: | Refer to figures |
| Synonyms: | IL9, HP40, IL-9, P40 |
| Background: | The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. |
| UniProt Protein Function: | IL9: Supports IL-2 independent and IL-4 independent growth of helper T-cells. Belongs to the IL-7/IL-9 family. |
| UniProt Protein Details: | Protein type:Secreted; Cytokine; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q31.1 Cellular Component: extracellular space Molecular Function:growth factor activity; interleukin-9 receptor binding; cytokine activity Biological Process: positive regulation of cell proliferation; immune response; inflammatory response; positive regulation of cell growth; positive regulation of interleukin-5 biosynthetic process |
| NCBI Summary: | The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P15248 |
| NCBI GenInfo Identifier: | 124362 |
| NCBI Gene ID: | 3578 |
| NCBI Accession: | P15248.1 |
| UniProt Related Accession: | P15248 |
| Molecular Weight: | 15kDa |
| NCBI Full Name: | Interleukin-9 |
| NCBI Synonym Full Names: | interleukin 9 |
| NCBI Official Symbol: | IL9 |
| NCBI Official Synonym Symbols: | P40; HP40; IL-9 |
| NCBI Protein Information: | interleukin-9; cytokine P40; p40 cytokine; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40 |
| UniProt Protein Name: | Interleukin-9 |
| UniProt Synonym Protein Names: | Cytokine P40; T-cell growth factor P40 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL9 |
| UniProt Entry Name: | IL9_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat lung using IL9 antibody (CAB1894) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon cancer using IL9 antibody (CAB1894) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach cancer using IL9 antibody (CAB1894) at dilution of 1:200 (40x lens). |
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