Immunology Antibodies 1
Anti-IL-36R Antibody (CAB10090)
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- SKU:
- CAB10090
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | IL36R Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB10090 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human IL36R (NP_003845.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, SW620, K-562, Mouse lung, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human IL36R (NP_003845.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MWSL LLCG LSIA LPLS VTAD GCKD IFMK NEIL SASQ PFAF NCTF PPIT SGEV SVTW YKNS SKIP VSKI IQSR IHQD ETWI LFLP MEWG DSGV YQCV IKGR DSCH RIHV NLTV FEKH |
| Gene ID: | 8808 |
| Uniprot: | Q9HB29 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 51kDa/65kDa |
| Observed MW: | 65kDa |
| Synonyms: | IL1RL2, IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2, IL36R |
| Background: | The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. |
| UniProt Protein Function: | IL1RL2: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2q12 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:interleukin-1 receptor activity Biological Process: cellular defense response; signal transduction |
| NCBI Summary: | The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HB29 |
| NCBI GenInfo Identifier: | 90110768 |
| NCBI Gene ID: | 8808 |
| NCBI Accession: | Q9HB29.2 |
| UniProt Secondary Accession: | Q9HB29,Q13525, Q45H74, Q53TU8, Q587I8, A4FU63, |
| UniProt Related Accession: | Q9HB29 |
| Molecular Weight: | 51,658 Da |
| NCBI Full Name: | Interleukin-1 receptor-like 2 |
| NCBI Synonym Full Names: | interleukin 1 receptor like 2 |
| NCBI Official Symbol: | IL1RL2 |
| NCBI Official Synonym Symbols: | IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2 |
| NCBI Protein Information: | interleukin-1 receptor-like 2 |
| UniProt Protein Name: | Interleukin-1 receptor-like 2 |
| UniProt Synonym Protein Names: | IL-36 receptor; IL-36R; Interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2 |
| Protein Family: | Interleukin-1 receptor |
| UniProt Gene Name: | IL1RL2 |
| UniProt Entry Name: | ILRL2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IL1RL2 antibody (CAB10090) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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