Immunology Antibodies 1
Anti-IL-1F10 Antibody (CAB13133)
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- SKU:
- CAB13133
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | IL1F10 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB13133 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human IL1F10 (NP_115945.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse kidney, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human IL1F10 (NP_115945.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MCSL PMAR YYII KYAD QKAL YTRD GQLL VGDP VADN CCAE KICI LPNR GLAR TKVP IFLG IQGG SRCL ACVE TEEG PSLQ LEDV NIEE LYKG GEEA TRFT FFQS SSGS AFRL EAAA WPGW FLCG PAEP QQPV QLTK ESEP SART KFYF EQSW |
| Gene ID: | 84639 |
| Uniprot: | Q8WWZ1 |
| Cellular Location: | Secreted |
| Calculated MW: | 16kDa |
| Observed MW: | 17kDa |
| Synonyms: | IL1F10, FIL1-theta, FKSG75, IL-1HY2, IL-38, IL1-theta, IL1HY2 |
| Background: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. |
| UniProt Protein Function: | IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 2q13 Cellular Component: extracellular space Molecular Function:interleukin-1 receptor binding; cytokine activity Biological Process: cytokine and chemokine mediated signaling pathway |
| NCBI Summary: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WWZ1 |
| NCBI GenInfo Identifier: | 25008589 |
| NCBI Gene ID: | 84639 |
| NCBI Accession: | Q8WWZ1.1 |
| UniProt Secondary Accession: | Q8WWZ1,Q53SR9, Q56AT8, Q7RTZ5, Q969H5, Q9BYX1, |
| UniProt Related Accession: | Q8WWZ1 |
| Molecular Weight: | 16,943 Da |
| NCBI Full Name: | Interleukin-1 family member 10 |
| NCBI Synonym Full Names: | interleukin 1 family, member 10 (theta) |
| NCBI Official Symbol: | IL1F10 |
| NCBI Official Synonym Symbols: | IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta |
| NCBI Protein Information: | interleukin-1 family member 10; FIL1 theta; IL-1 theta; interleukin-38; interleukin-1 HY2; family of interleukin 1-theta; IL-1F10 (canonical form IL-1F10a); interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta |
| UniProt Protein Name: | Interleukin-1 family member 10 |
| UniProt Synonym Protein Names: | Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38 |
| UniProt Gene Name: | IL1F10 |
| UniProt Entry Name: | IL1FA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IL1F10 antibody (CAB13133) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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