Immunology Antibodies 1
Anti-IL-17RE Antibody (CAB14315)
(No reviews yet)
Write a Review
- SKU:
- CAB14315
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | IL17RE Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB14315 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_705613.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HT-29, A-549, A-431, Mouse kidney, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_705613.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AGIG FRHL PHWN TRCP LASH TDDS FTGS SAYI PCRT WWAL FSTK PWCV RVWH CSRC LCQH LLSG GSGL QRGL FHLL VQKS KKSS TFKF YRRH KMPA PAQR KLLP RRHL SEKS HHIS IPSP DISH KGLR SKRT QPSD PETW ESLP RLDS QRHG GPEF SFDL LPEA RAIR VTIS SGPE VSVR LCHQ WALE CEEL SSPY DVQK IVSG GHTV ELPY EFLL PCLC IEAS YLQE DTVR RKKC P |
| Gene ID: | 132014 |
| Uniprot: | Q8NFR9 |
| Cellular Location: | Cell membrane, Cytoplasm, Secreted, Single-pass type I membrane protein |
| Calculated MW: | 30kDa/43kDa/58kDa/61kDa/74kDa |
| Observed MW: | 75kDa |
| Synonyms: | IL17RE |
| Background: | This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. |
| UniProt Protein Function: | IL17RE: Receptor which can activate the MAPK signaling pathway and seems to function at or upstream of Ras. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 3p25.3 Cellular Component: integral to plasma membrane; cytoplasm; extracellular region Molecular Function:protein binding; interleukin-17 receptor activity Biological Process: cytokine and chemokine mediated signaling pathway; inflammatory response |
| NCBI Summary: | This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q8NFR9 |
| NCBI GenInfo Identifier: | 24430204 |
| NCBI Gene ID: | 132014 |
| NCBI Accession: | NP_705613.1 |
| UniProt Secondary Accession: | Q8NFR9,Q6P532, Q8N8H7, Q8N8H8, Q8TEC2, B2RB34, B2RNR1 B9EH65, |
| UniProt Related Accession: | Q8NFR9 |
| Molecular Weight: | 30,781 Da |
| NCBI Full Name: | interleukin-17 receptor E isoform 1 |
| NCBI Synonym Full Names: | interleukin 17 receptor E |
| NCBI Official Symbol: | IL17RE |
| NCBI Protein Information: | interleukin-17 receptor E; IL-17 receptor E |
| UniProt Protein Name: | Interleukin-17 receptor E |
| Protein Family: | Interleukin-17 receptor |
| UniProt Gene Name: | IL17RE |
| UniProt Entry Name: | I17RE_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IL17RE antibody (CAB14315) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
View AllClose
Related Products
