Cell Biology Antibodies 1
Anti-IL-17RD Antibody (CAB10031)
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- SKU:
- CAB10031
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | IL17RD Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB10031 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human IL17RD (NP_060033.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HT-29, U-87MG, Mouse brain, Mouse kidney, Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human IL17RD (NP_060033.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FLNM KFET DYFV KVVP FPSI KNES NYHP FFFR TRAC DLLL QPDN LACK PFWK PRNL NISQ HGSD MQVS FDHA PHNF GFRF FYLH YKLK HEGP FKRK TCKQ EQTT ETTS CLLQ NVSP GDYI IELV DDTN TTRK VMHY ALKP VHSP WAGP IRA |
| Gene ID: | 54756 |
| Uniprot: | Q8NFM7 |
| Cellular Location: | Cell membrane, Cytoplasm, Golgi apparatus membrane, Single-pass type I membrane protein, Single-pass type I membrane protein |
| Calculated MW: | 66kDa/79kDa/82kDa |
| Observed MW: | 110kDa |
| Synonyms: | IL17RD, HH18, IL-17RD, IL17RLM, SEF |
| Background: | This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. |
| NCBI Summary: | This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q8NFM7 |
| NCBI GenInfo Identifier: | 124494234 |
| NCBI Gene ID: | 54756 |
| NCBI Accession: | NP_001074442 |
| UniProt Related Accession: | Q8NFM7 |
| Molecular Weight: | |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | interleukin 17 receptor D |
| NCBI Official Symbol: | IL17RD |
| NCBI Official Synonym Symbols: | SEF; HH18; IL-17RD; IL17RLM |
| NCBI Protein Information: | interleukin-17 receptor D |
| UniProt Protein Name: | Interleukin-17 receptor D |
| UniProt Synonym Protein Names: | IL17Rhom; Interleukin-17 receptor-like protein; Sef homolog; hSef |
| UniProt Gene Name: | IL17RD |
| UniProt Entry Name: | I17RD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IL17RD antibody (CAB10031) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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