Epigenetics & Nuclear Signaling Antibodies 1

Anti-IKZF2 Antibody (CAB12265)

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SKU:
CAB12265
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-IKZF2 Antibody
Antibody SKU:CAB12265
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:K-562, HeLa, Mouse thymus, Rat thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TYLG AEAL HPLM QHPP STIA EVAP VISS AYSQ VYHP NRIE RPIS RETA DSHE NNMD GPIS LIRP KSRP QERE ASPS NSCL DSTD SESS HDDH QSYQ GHPA LNPK RKQS PAYM KEDV KALD TTKA PKGS LKDI YKVF NGEG E
Gene ID:22807
Uniprot:Q9UKS7
Cellular Location:Nucleus
Calculated MW:5kDa/16kDa/25kDa/26kDa/51kDa/56kDa/59kDa
Observed MW:60kDa
Synonyms:IKZF2, ANF1A2, HELIOS, ZNF1A2, ZNFN1A2
Background:This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
UniProt Protein Function:Associates with Ikaros at centromeric heterochromatin.
NCBI Summary:This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UKS7
NCBI GenInfo Identifier:116242509
NCBI Gene ID:22807
NCBI Accession:Q9UKS7.2
UniProt Secondary Accession:Q9UKS7,Q53YJ5, Q6PQC5, Q6PQC6, Q6PQC7, Q6PQC8, Q6PQD0 Q6PQD1, Q8N6S1,
UniProt Related Accession:Q9UKS7
Molecular Weight:60kDa
NCBI Full Name:Zinc finger protein Helios
NCBI Synonym Full Names:IKAROS family zinc finger 2
NCBI Official Symbol:IKZF2  
NCBI Official Synonym Symbols:ANF1A2; HELIOS; ZNF1A2; ZNFN1A2  
NCBI Protein Information:zinc finger protein Helios
UniProt Protein Name:Zinc finger protein Helios
UniProt Synonym Protein Names:Ikaros family zinc finger protein 2
Protein Family:Zinc finger protein
UniProt Gene Name:IKZF2  
Anti-IKZF2 Antibody (CAB12265)Western blot analysis of extracts of various cell lines, using IKZF2 antibody (CAB12265) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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