Anti-IGFBP2 Antibody (CAB9018)
- SKU:
- CAB9018
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IBP2
- Synonyms:
- IGF-BP53
- Research Area:
- Developmental Biology
Description
| Product Name: | IGFBP2 Rabbit mAb |
| Product Code: | CAB9018 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | IBP2, IGF-BP53 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human IGFBP2 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | HepG2, PC-3 |
| Immunogen: | A synthesized peptide derived from human IGFBP2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3485 |
| Uniprot: | P18065 |
| Calculated MW: | 35kDa |
| Observed MW: | 35KDa |
| UniProt Protein Function: | IGFBP2: Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Binds IGF2 more than IGF1. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q35 Cellular Component: extracellular space; apical plasma membrane; extracellular region; cytoplasmic vesicle Molecular Function:protein binding; insulin-like growth factor I binding; insulin-like growth factor II binding Biological Process: response to drug; regulation of insulin-like growth factor receptor signaling pathway; response to retinoic acid; response to lithium ion; response to glucocorticoid stimulus; female pregnancy; positive regulation of activated T cell proliferation; signal transduction; response to estradiol stimulus; cellular response to hormone stimulus; cellular protein metabolic process; response to mechanical stimulus; regulation of cell growth; response to nutrient; aging |
| UniProt Code: | P18065 |
| NCBI GenInfo Identifier: | 290457647 |
| NCBI Gene ID: | 3485 |
| NCBI Accession: | P18065.2 |
| UniProt Secondary Accession: | P18065,Q14619, Q9UCL3, |
| UniProt Related Accession: | P18065 |
| Molecular Weight: | 34,814 Da |
| NCBI Full Name: | Insulin-like growth factor-binding protein 2 |
| NCBI Synonym Full Names: | insulin-like growth factor binding protein 2, 36kDa |
| NCBI Official Symbol: | IGFBP2 |
| NCBI Official Synonym Symbols: | IBP2; IGF-BP53 |
| NCBI Protein Information: | insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2 |
| UniProt Protein Name: | Insulin-like growth factor-binding protein 2 |
| Protein Family: | Insulin-like growth factor-binding protein |
| UniProt Gene Name: | IGFBP2 |
| UniProt Entry Name: | IBP2_HUMAN |
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