Metabolism Antibodies 2
Anti-IGF2 Antibody (CAB2086)
- SKU:
- CAB2086
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-IGF2 Antibody |
| Antibody SKU: | CAB2086 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human IGF2 (NP_000603.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, SW480, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human IGF2 (NP_000603.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AYRP SETL CGGE LVDT LQFV CGDR GFYF SRPA SRVS RRSR GIVE ECCF RSCD LALL ETYC ATPA KSER DVST PPTV LPDN FPRY PVGK FFQY DTWK QSTQ RLRR GLPA LLRA RRGH VLAK ELEA FREA KRHR PLIA LPTQ DPAH GGAP PEMA SNRK |
| Gene ID: | 3481 |
| Uniprot: | P01344 |
| Cellular Location: | Secreted |
| Calculated MW: | 20kDa/26kDa |
| Observed MW: | 28kDa |
| Synonyms: | IGF2, C11orf43, GRDF, IGF-II, PP9974 |
| Background: | This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| UniProt Code: | P01344 |
| NCBI GenInfo Identifier: | 124255 |
| NCBI Gene ID: | 3481 |
| NCBI Accession: | P01344.1 |
| UniProt Related Accession: | P01344 |
| Molecular Weight: | 11kDa |
| NCBI Full Name: | Insulin-like growth factor II |
| NCBI Synonym Full Names: | insulin like growth factor 2 |
| NCBI Official Symbol: | IGF2 |
| NCBI Official Synonym Symbols: | GRDF; IGF-II; PP9974; C11orf43 |
| NCBI Protein Information: | insulin-like growth factor II |
| UniProt Protein Name: | Insulin-like growth factor II |
| UniProt Synonym Protein Names: | Somatomedin-ACleaved into the following 3 chains:Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin |
| Protein Family: | Insulin-like growth factor |
| UniProt Gene Name: | IGF2 |
| UniProt Entry Name: | IGF2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IGF2 antibody (CAB2086) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded human placenta using IGF2 Rabbit pAb (CAB2086) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A-549 cells using IGF2 antibody (CAB2086). Blue: DAPI for nuclear staining. |
View AllClose
Related Products
IGF2 Polyclonal Antibody
OverviewProduct Name:IGF2 Polyclonal AntibodyProduct Code:CAB24842Reactivity:Human, Mouse, RatApplications:Immunofluorescence
Anti-PNMT Antibody (CAB20862)
OverviewAntibody Name:Anti-PNMT Antibody (CAB20862)Antibody SKU:CAB20862Antibody Size:50µL, 100µLApplication:Western blotting, Immunofluorescence
Anti-HNF-4-alpha Antibody (CAB20865)
OverviewAntibody Name:Anti-HNF-4-alpha Antibody (CAB20865)Antibody SKU:CAB20865Antibody Size:50µL, 100µLApplication:Western blotting, Immunohistochemistr
Anti-Lactate Dehydrogenase C Antibody (CAB20866)
OverviewAntibody Name:Anti-Lactate Dehydrogenase C Antibody (CAB20866)Antibody SKU:CAB20866Antibody Size:50µL, 100µLApplication:Western blotting