Anti-IGF1R Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0332)
- SKU:
- HDAB0332
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit/Human Fc chimeric IgG1
- Clone:
- DMC684
- Synonyms:
- CD221, IGFIR, IGFR, JTK13
Description
system_update_altDatasheet
SKU: | HDAB0332 |
Size: | 100 µg |
Clonality: | Monoclonal |
Clone: | DMC684 |
Synonyms: | CD221; IGFIR; IGFR; JTK13 |
Applications: | Flow Cyt |
Recommended Dilution: | Flow Cyt 1:100 |
Host Species: | Rabbit |
Isotype: | Rabbit/Human Fc chimeric IgG1 |
Reactivity: | Human |
Purification Method: | Purified from cell culture supernatant by affinity chromatography |
Formulation: | Powder |
Buffer: | 1XPBS |
Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Usage: | Research use only |
Background: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |