Immunology Antibodies 2

Anti-IFNA21 Antibody (CAB16881)

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SKU:
CAB16881
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-IFNA21 Antibody
Antibody SKU:CAB16881
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human IFNA21 (NP_002166.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human IFNA21 (NP_002166.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:WEQS LLEK FSTE LNQQ LNDL EACV IQEV GVEE TPLM NVDS ILAV KKYF QRIT LYLT EKKY SPCA WEVV RAEI MRSF SLSK IFQE RLRR KE
Gene ID:3452
Uniprot:P01568
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:IFNA21, IFN-alphaI, LeIF F, leIF-F
Background:This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus.
UniProt Protein Function:IFNA21: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.
UniProt Protein Details:

Protein type:Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21.3

Cellular Component: extracellular region; extracellular space

Molecular Function:cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding

Biological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response

NCBI Summary:This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]
UniProt Code:P01568
NCBI GenInfo Identifier:169791013
NCBI Gene ID:3452
NCBI Accession:NP_002166.2
UniProt Secondary Accession:P01568,Q14608, Q5VWD1, Q7M4Q4,
UniProt Related Accession:P01568
Molecular Weight:21.3kD
NCBI Full Name:interferon alpha-21
NCBI Synonym Full Names:interferon alpha 21
NCBI Official Symbol:IFNA21  
NCBI Official Synonym Symbols:LeIF F; leIF-F; IFN-alphaI  
NCBI Protein Information:interferon alpha-21
UniProt Protein Name:Interferon alpha-21
UniProt Synonym Protein Names:Interferon alpha-F; LeIF F
Protein Family:Interferon
UniProt Gene Name:IFNA21  
Anti-IFNA21 Antibody (CAB16881)Western blot analysis of extracts of mouse thymus, using IFNA21 antibody (CAB16881) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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