Name: Anti-IFI6 Antibody (CAB6157)
Brand: Immunology Antibodies 2
SKU: CAB6157
Availability: OutOfStock

Antibody Name:	Anti-IFI6 Antibody
Antibody SKU:	CAB6157
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human IFI6 (NP_002029.3).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	22Rv1, MCF7, U-251MG, U-937, Mouse pancreas

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human IFI6 (NP_002029.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MRQK AVSL FLCY LLLF TCSG VEAG KKKC SESS DSGS GFWK ALTF MAVG GGLA VAGL PALG FTGA GIAA NSVA ASLM SWSA ILNG GGVP AGGL VATL QSLG AGGS SVVI GNIG ALMG YATH KYLD SEED EE
Gene ID:	2537
Uniprot:	P09912
Cellular Location:	Membrane, Multi-pass membrane protein
Calculated MW:	12kDa/13kDa
Observed MW:	15kDa

Synonyms:

IFI6, 6-16, FAM14C, G1P3, IFI-6-16, IFI616

Background:

This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

UniProt Protein Function:	IFI6: first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Protein type:Membrane protein, multi-pass; Apoptosis; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p35 Cellular Component: mitochondrion; plasma membrane; integral to membrane Molecular Function:protein binding Biological Process: release of cytochrome c from mitochondria; cytokine and chemokine mediated signaling pathway; immune response; negative regulation of caspase activity; negative regulation of mitochondrial depolarization
NCBI Summary:	This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008]
UniProt Code:	P09912
NCBI GenInfo Identifier:	20178294
NCBI Gene ID:	2537
NCBI Accession:	P09912.2
UniProt Secondary Accession:	P09912,Q13141, Q13142, Q5VVR2, Q5VVR3, Q6IE95, Q969M8
UniProt Related Accession:	P09912
Molecular Weight:	130
NCBI Full Name:	Interferon alpha-inducible protein 6
NCBI Synonym Full Names:	interferon, alpha-inducible protein 6
NCBI Official Symbol:	IFI6
NCBI Official Synonym Symbols:	6-16; G1P3; FAM14C; IFI616; IFI-6-16
NCBI Protein Information:	interferon alpha-inducible protein 6; interferon-induced protein 6-16; interferon, alpha-inducible protein clone IFI-6-16
UniProt Protein Name:	Interferon alpha-inducible protein 6
UniProt Synonym Protein Names:	Interferon-induced protein 6-16; Ifi-6-16
Protein Family:	Interferon alpha-inducible protein
UniProt Gene Name:	IFI6
UniProt Entry Name:	IFI6_HUMAN

Western blot analysis of extracts of various cell lines, using IFI6 antibody (CAB6157) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 40s.

ELISA Kits

Human Interferon alpha-inducible protein 6 / IFI6 ELISA Kit

Human Interferon alpha-inducible protein 6 (IFI6) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)