Immunology Antibodies 1

Anti-IFI27 Antibody (CAB14174)

(No reviews yet) Write a Review
SKU:
CAB14174
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-IFI27 Antibody
Antibody SKU:CAB14174
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:Rat heart
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEAS ALTS SAVT SVAK VVRV ASGS AVVL PLAR IATV VIGG VVAV PMVL SAMG FTAA GIAS SSIA AKMM SAAA IANG GGVA SGSL VATL QSLG ATGL SGLT
Gene ID:3429
Uniprot:P40305
Cellular Location:Membrane, Mitochondrion, Multi-pass membrane protein
Calculated MW:11kDa
Observed MW:11kDa
Synonyms:IFI27, FAM14D, ISG12, ISG12A, P27
Background:
UniProt Protein Function:IFI27: Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Belongs to the IFI6/IFI27 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion; nuclear inner membrane

Molecular Function:lamin binding

Biological Process: caspase activation; negative regulation of transcription from RNA polymerase II promoter; regulation of protein export from nucleus

UniProt Code:P40305
NCBI GenInfo Identifier:55925614
NCBI Gene ID:3429
NCBI Accession:NP_005523.3
UniProt Secondary Accession:P40305,Q53YA6, Q6IEC1, Q96BK3,
UniProt Related Accession:P40305
Molecular Weight:
NCBI Full Name:interferon alpha-inducible protein 27, mitochondrial isoform 2
NCBI Synonym Full Names:interferon alpha inducible protein 27
NCBI Official Symbol:IFI27  
NCBI Official Synonym Symbols:P27; ISG12; FAM14D; ISG12A  
NCBI Protein Information:interferon alpha-inducible protein 27, mitochondrial
UniProt Protein Name:Interferon alpha-inducible protein 27, mitochondrial
UniProt Synonym Protein Names:Interferon alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a)
Protein Family:Interferon alpha-inducible protein
UniProt Gene Name:IFI27  
UniProt Entry Name:IFI27_HUMAN
Anti-IFI27 Antibody (CAB14174)Western blot analysis of extracts of rat heart, using IFI27 antibody (CAB14174) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products