Name: Anti-ICAM5 Antibody (CAB4156)
Brand: Cell Biology Antibodies 9
SKU: CAB4156
Availability: OutOfStock

Antibody Name:	Anti-ICAM5 Antibody
Antibody SKU:	CAB4156
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 32-180 of human ICAM5 (NP_003250.3).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse brain, Rat testis

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 32-180 of human ICAM5 (NP_003250.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EPFW ADLQ PRVA FVER GGSL WLNC STNC PRPE RGGL ETSL RRNG TQRG LRWL ARQL VDIR EPET QPVC FFRC ARRT LQAR GLIR TFQR PDRV ELMP LPPW QPVG ENFT LSCR VPGA GPRA SLTL TLLR GAQE LIRR SFAG EPPR ARGA V
Gene ID:	7087
Uniprot:	Q9UMF0
Cellular Location:	Membrane, Single-pass type I membrane protein
Calculated MW:	97kDa
Observed MW:	115kDa

Synonyms:

ICAM5, TLCN, TLN

Background:

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

UniProt Protein Function:	ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family.
UniProt Protein Details:	Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:integrin binding; protein binding Biological Process: cell-cell adhesion; cell adhesion; phagocytosis
NCBI Summary:	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9UMF0
NCBI GenInfo Identifier:	296439327
NCBI Gene ID:	7087
NCBI Accession:	Q9UMF0.3
UniProt Related Accession:	Q9UMF0
Molecular Weight:	97kDa
NCBI Full Name:	Intercellular adhesion molecule 5
NCBI Synonym Full Names:	intercellular adhesion molecule 5
NCBI Official Symbol:	ICAM5
NCBI Official Synonym Symbols:	TLN; TLCN
NCBI Protein Information:	intercellular adhesion molecule 5
UniProt Protein Name:	Intercellular adhesion molecule 5
UniProt Synonym Protein Names:	Telencephalin
Protein Family:	Intercellular adhesion molecule
UniProt Gene Name:	ICAM5
UniProt Entry Name:	ICAM5_HUMAN

Western blot analysis of extracts of various cell lines, using ICAM5 Antibody (CAB4156) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Antibodies

ICAM5 Antibody (PACO09855)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)