Cell Biology Antibodies 13
Anti-ICA1 Antibody (CAB17500)
- SKU:
- CAB17500
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-ICA1 Antibody |
Antibody SKU: | CAB17500 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ICA1 (NP_001263407). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human |
Positive Samples: | U-87MG, BxPC-3 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ICA1 (NP_001263407). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MSGH KCYP WDLQ DRYA QDKS VVNK MQQK YWET KQAF IKAT GKKE DEHV VASD ADLD AKLE LFHS IQRT CLDL SKAI VLYQ KRIC FLSQ EENE LGKF LRSQ GFQD KTRA GKMM QATG KALC FSSQ QRLA LRNP LCRF HQEV ETFR HRAI SDTW LTVN RMEQ |
Gene ID: | 3382 |
Uniprot: | Q05084 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 69kDa |
Synonyms: | ICA69, ICAp69, ICA1 |
Background: | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |
UniProt Protein Function: | ICA1: May play a role in neurotransmitter secretion. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 7p22 Cellular Component: cytoplasm; cytosol; Golgi apparatus; Golgi membrane; secretory granule membrane; synaptic vesicle membrane Molecular Function:protein binding |
NCBI Summary: | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |
UniProt Code: | Q05084 |
NCBI GenInfo Identifier: | 20141584 |
NCBI Gene ID: | 3382 |
NCBI Accession: | Q05084.2 |
UniProt Secondary Accession: | Q05084,P78506, Q13824, Q96HG3, A8K7U1, B3FTQ2, |
UniProt Related Accession: | Q05084 |
Molecular Weight: | 54,558 Da |
NCBI Full Name: | Islet cell autoantigen 1 |
NCBI Synonym Full Names: | islet cell autoantigen 1 |
NCBI Official Symbol: | ICA1 |
NCBI Official Synonym Symbols: | ICA69; ICAp69 |
NCBI Protein Information: | islet cell autoantigen 1 |
UniProt Protein Name: | Islet cell autoantigen 1 |
UniProt Synonym Protein Names: | 69 kDa islet cell autoantigen; ICA69; Islet cell autoantigen p69; ICAp69; p69 |
Protein Family: | Islet cell autoantigen |
UniProt Gene Name: | ICA1 |
UniProt Entry Name: | ICA69_HUMAN |