Cell Biology Antibodies 10

Anti-HUS1B Antibody (CAB6817)

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SKU:
CAB6817
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-HUS1B Antibody
Antibody SKU:CAB6817
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human HUS1B (NP_683762.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, Jurkat, Mouse spleen, Mouse thymus, Rat testis, Rat thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human HUS1B (NP_683762.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKFR AKIT GKGC LELF IHVS GTVA RLAK VCVL RVRP DSLC FGPA GSGG LHEA RLWC EVRQ GAFQ QFRM EGVS EDLD EIHL ELTA EHLS RAAR SAAG ASSL KLQL THKR RPSL TVAV ELVS SLGR ARSV VHDL PVRV LPRR VWRD CLPP SLRA SDAS IRLP RWRT LRSI VERM ANVG SHVL VEAN LSGR MTLS IETE VVSI QSYF KNLG NPPQ SAVG VPEN RDLE SMVQ VRVD NRKL LQFL EGQQ IHPT TALC NIWD NTLL QLVL VQED VSLQ YFIP AL
Gene ID:135458
Uniprot:Q8NHY5
Cellular Location:
Calculated MW:30kDa
Observed MW:31kDa
Synonyms:HUS1B
Background:The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
UniProt Protein Function:HUS1B: is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Cell cycle regulation

Chromosomal Location of Human Ortholog: 6p25.3

Cellular Component: nucleolus

Biological Process: DNA damage checkpoint; DNA repair

NCBI Summary:The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008]
UniProt Code:Q8NHY5
NCBI GenInfo Identifier:311033394
NCBI Gene ID:135458
NCBI Accession:Q8NHY5.2
UniProt Secondary Accession:Q8NHY5,Q5T4Z2,
UniProt Related Accession:Q8NHY5
Molecular Weight:278
NCBI Full Name:Checkpoint protein HUS1B
NCBI Synonym Full Names:HUS1 checkpoint homolog b (S. pombe)
NCBI Official Symbol:HUS1B  
NCBI Protein Information:checkpoint protein HUS1B; hHUS1B
UniProt Protein Name:Checkpoint protein HUS1B
Protein Family:Checkpoint protein
UniProt Gene Name:HUS1B  
UniProt Entry Name:HUS1B_HUMAN
Anti-HUS1B Antibody (CAB6817)Western blot analysis of extracts of various cell lines, using HUS1B antibody (CAB6817) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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