Cell Biology Antibodies 13

Anti-HTR5A Antibody (CAB17499)

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SKU:
CAB17499
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-HTR5A Antibody
Antibody SKU:CAB17499
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-285 of human HTR5A (NP_076917.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-285 of human HTR5A (NP_076917.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:YWKI YKAA KFRV GSRK TNSV SPIS EAVE VKDS AKQP QMVF TVRH ATVT FQPE GDTW REQK EQRA AL
Gene ID:3361
Uniprot:P47898
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:5-HT5A, HTR5A
Background:The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
UniProt Protein Function:5-HT(5A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: plasma membrane

Molecular Function:serotonin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

NCBI Summary:The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
UniProt Code:P47898
NCBI GenInfo Identifier:1345607
NCBI Gene ID:3361
NCBI Accession:P47898.1
UniProt Secondary Accession:P47898,Q2M2D2,
UniProt Related Accession:P47898
Molecular Weight:40,255 Da
NCBI Full Name:5-hydroxytryptamine receptor 5A
NCBI Synonym Full Names:5-hydroxytryptamine receptor 5A
NCBI Official Symbol:HTR5A  
NCBI Official Synonym Symbols:5-HT5A  
NCBI Protein Information:5-hydroxytryptamine receptor 5A
UniProt Protein Name:5-hydroxytryptamine receptor 5A
UniProt Synonym Protein Names:Serotonin receptor 5A
Protein Family:5-hydroxytryptamine receptor
UniProt Gene Name:HTR5A  
UniProt Entry Name:5HT5A_HUMAN
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