Anti-HTR4 Antibody (CAB2802)
- SKU:
- CAB2802
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HTR4
- Synonyms:
- 5-HT4
- Synonyms:
- 5-HT4R
Description
| Product Name: | HTR4 Rabbit pAb |
| Product Code: | CAB2802 |
| Size: | 100uL |
| Synonyms: | HTR4, 5-HT4, 5-HT4R |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human HTR4. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, Mouse brain, Rat brain, small intestine |
| Immunogen: | Recombinant protein of human HTR4. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3360 |
| Uniprot: | Q13639 |
| Cellular Location: | Cell membrane, Endosome, Multi-pass membrane protein |
| Calculated MW: | 40kDa/42kDa/43kDa/44kDa/45kDa/46kDa/48kDa |
| Observed MW: | 44KDa |
| UniProt Protein Function: | 5-HT(4): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 8 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 5q32 Cellular Component: cytoplasm; membrane; plasma membrane Molecular Function:serotonin receptor activity; trace-amine receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; gamma-aminobutyric acid signaling pathway |
| NCBI Summary: | This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] |
| UniProt Code: | Q13639 |
| NCBI GenInfo Identifier: | 12644029 |
| NCBI Gene ID: | 3360 |
| NCBI Accession: | Q13639.2 |
| UniProt Secondary Accession: | Q13639,Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199 Q9NY73, Q9UBM6, Q9UBT4, Q9UE22, C4WYH4, |
| UniProt Related Accession: | Q13639 |
| Molecular Weight: | 44kDa |
| NCBI Full Name: | 5-hydroxytryptamine receptor 4 |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 4 |
| NCBI Official Symbol: | HTR4 |
| NCBI Official Synonym Symbols: | 5-HT4; 5-HT4R |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 4 |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 4 |
| UniProt Synonym Protein Names: | Serotonin receptor 4 |
| Protein Family: | Transducer protein |
| UniProt Gene Name: | HTR4 |
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