Cell Biology Antibodies 9
Anti-HSPBP1 Antibody (CAB4574)
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- SKU:
- CAB4574
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HSPBP1
- Synonyms:
- FES1
- Research Area:
- Cell Biology
Description
| Product Name: | HSPBP1 Rabbit pAb |
| Product Code: | CAB4574 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | HSPBP1, FES1 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human HSPBP1 (NP_036399.3). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human HSPBP1 (NP_036399.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSDE GSRG SRLP LALP PASQ GCSS GGGG GGSS AGGS GNSR PPRN LQGL LQMA ITAG SEEP DPPP EPMS EERR QWLQ EAMS AAFR GQRE EVEQ MKSC LRVL SQPM PPTA GEAE QAAD QQER EGAL ELLA DLCE NMDN AADF CQLS GMHL LVGR YLEA GAAG LRWR AAQL IGTC SQNV AAIQ EQVL GLGA LRKL LRLL DRDA CDTV RVKA LFAI SCLV REQE AGLL QFLR LDGF SVLM RAMQ QQVQ KLKV KSAF LLQN LLVG HPEH KGTL CSMG MVQQ LVAL VRTE HSPF HEHV LGAL CSLV TDFP QGVR ECRE PELG LEEL LRHR CQLL QQHE EYQE ELEF CEKL LQTC FSSP ADDS MDR |
| Gene ID: | 23640 |
| Uniprot: | Q9NZL4 |
| Calculated MW: | 28kDa/39kDa/44kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | HSPBP1: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.42 Molecular Function:enzyme inhibitor activity; protein binding Biological Process: protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of catalytic activity |
| UniProt Code: | Q9NZL4 |
| NCBI GenInfo Identifier: | 74734730 |
| NCBI Gene ID: | 23640 |
| NCBI Accession: | Q9NZL4.1 |
| UniProt Secondary Accession: | Q9NZL4,O95351, Q6ZNU5, B3KQP0, B4DG11, |
| UniProt Related Accession: | Q9NZL4 |
| Molecular Weight: | 362 |
| NCBI Full Name: | Hsp70-binding protein 1 |
| NCBI Synonym Full Names: | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| NCBI Official Symbol: | HSPBP1 |
| NCBI Official Synonym Symbols: | FES1 |
| NCBI Protein Information: | hsp70-binding protein 1; hsp70 interacting protein; heat shock protein-binding protein 1 |
| UniProt Protein Name: | Hsp70-binding protein 1 |
| UniProt Synonym Protein Names: | Heat shock protein-binding protein 1; Hsp70-binding protein 2; HspBP2; Hsp70-interacting protein 1; Hsp70-interacting protein 2 |
| Protein Family: | Hsp70-binding protein |
| UniProt Gene Name: | HSPBP1 |
| UniProt Entry Name: | HPBP1_HUMAN |
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