Metabolism Antibodies 2

Anti-HSPA6 Antibody (CAB7688)

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SKU:
CAB7688
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-HSPA6 Antibody
Antibody SKU:CAB7688
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, Mouse heart, Rat brain, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PQIE VTFD IDAN GILS VTAT DRST GKAN KITI TNDK GRLS KEEV ERMV HEAE QYKA EDEA QRDR VAAK NSLE AHVF HVKG SLQE ESLR DKIP EEDR RKMQ DKCR EVLA WLEH NQLA EKEE YEHQ KREL EQIC RPIF SRLY GGPG VPGG SSCG TQAR QGDP STGP IIEE VD
Gene ID:3310
Uniprot:P17066
Cellular Location:
Calculated MW:71kDa
Observed MW:71kDa
Synonyms:HSPA6, HSP70B
Background:
UniProt Protein Function:HSPA6: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Belongs to the heat shock protein 70 family.
UniProt Protein Details:

Protein type:Heat shock protein

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: centriole; cytoplasm; cytosol; signalosome

Molecular Function:ATPase activity, coupled; enzyme binding; heat shock protein binding; protein binding; unfolded protein binding

Biological Process: protein refolding; response to unfolded protein

UniProt Code:P17066
NCBI GenInfo Identifier:34978357
NCBI Gene ID:3310
NCBI Accession:P17066.2
UniProt Secondary Accession:P17066,Q1HBA8, Q8IYK7, Q9BT95,
UniProt Related Accession:P17066
Molecular Weight:71,028 Da
NCBI Full Name:Heat shock 70 kDa protein 6
NCBI Synonym Full Names:heat shock protein family A (Hsp70) member 6
NCBI Official Symbol:HSPA6  
NCBI Official Synonym Symbols:HSP70B'  
NCBI Protein Information:heat shock 70 kDa protein 6
UniProt Protein Name:Heat shock 70 kDa protein 6
UniProt Synonym Protein Names:Heat shock 70 kDa protein B'
Protein Family:Heat shock 70 kDa protein
UniProt Gene Name:HSPA6  
UniProt Entry Name:HSP76_HUMAN
Anti-HSPA6 Antibody (CAB7688)Western blot analysis of extracts of various cell lines, using HSPA6 antibody (CAB7688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-HSPA6 Antibody (CAB7688)Immunohistochemistry of paraffin-embedded human liver using HSPA6 Rabbit pAb (CAB7688) at dilution of 1:100 (40x lens).
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