Cell Biology Antibodies 13

Anti-HSPA4L Antibody (CAB17637)

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SKU:
CAB17637
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-HSPA4L Antibody
Antibody SKU:CAB17637
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 500-600 of human HSPA4L (NP_055093.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, K-562, HeLa, Mouse brain, Rat testis, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 500-600 of human HSPA4L (NP_055093.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KQNL EGDH SDAP METE TSFK NENK DNMD KMQV DQEE GHQK CHAE HTPE EEID HTGA KTKS AVSD KQDR LNQT LKKG KVKS IDLP IQSS LCRQ LGQD LLNS Y
Gene ID:22824
Uniprot:O95757
Cellular Location:
Calculated MW:
Observed MW:115kDa
Anti-HSPA4L Antibody (CAB17637)Western blot - HSPA4L Polyclonal Antibody (CAB17637)
Synonyms:APG-1, HSPH3, Osp94, HSPA4L
Background:The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
UniProt Protein Function:HSPA4L: a heat shock protein of the HSP110 family. Expressed ubiquitously and predominantly in the testis. Highly expressed by leukemia cells, and elicits humoral immune responses in leukemia patients.
UniProt Protein Details:

Protein type:Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 4q28

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function:ATP binding

Biological Process: protein folding; response to unfolded protein

NCBI Summary:The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
UniProt Code:O95757
NCBI GenInfo Identifier:311033441
NCBI Gene ID:22824
NCBI Accession:O95757.3
UniProt Secondary Accession:O95757,Q4W5M5, Q8IWA2, A2ICT2,
UniProt Related Accession:O95757
Molecular Weight:94,512 Da
NCBI Full Name:Heat shock 70 kDa protein 4L
NCBI Synonym Full Names:heat shock protein family A (Hsp70) member 4 like
NCBI Official Symbol:HSPA4L  
NCBI Official Synonym Symbols:APG-1; HSPH3; Osp94  
NCBI Protein Information:heat shock 70 kDa protein 4L
UniProt Protein Name:Heat shock 70 kDa protein 4L
UniProt Synonym Protein Names:Heat shock 70-related protein APG-1; Osmotic stress protein 94
Protein Family:Heat shock 70 kDa protein
UniProt Gene Name:HSPA4L  
UniProt Entry Name:HS74L_HUMAN
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