Cell Biology Antibodies 13
Anti-HSPA4L Antibody (CAB17637)
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- SKU:
- CAB17637
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HSPA4L Antibody |
| Antibody SKU: | CAB17637 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-600 of human HSPA4L (NP_055093.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, K-562, HeLa, Mouse brain, Rat testis, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-600 of human HSPA4L (NP_055093.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KQNL EGDH SDAP METE TSFK NENK DNMD KMQV DQEE GHQK CHAE HTPE EEID HTGA KTKS AVSD KQDR LNQT LKKG KVKS IDLP IQSS LCRQ LGQD LLNS Y |
| Gene ID: | 22824 |
| Uniprot: | O95757 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 115kDa |
 | Western blot - HSPA4L Polyclonal Antibody (CAB17637) |
| Synonyms: | APG-1, HSPH3, Osp94, HSPA4L |
| Background: | The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| UniProt Protein Function: | HSPA4L: a heat shock protein of the HSP110 family. Expressed ubiquitously and predominantly in the testis. Highly expressed by leukemia cells, and elicits humoral immune responses in leukemia patients. |
| UniProt Protein Details: | Protein type:Heat shock protein; Chaperone Chromosomal Location of Human Ortholog: 4q28 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:ATP binding Biological Process: protein folding; response to unfolded protein |
| NCBI Summary: | The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| UniProt Code: | O95757 |
| NCBI GenInfo Identifier: | 311033441 |
| NCBI Gene ID: | 22824 |
| NCBI Accession: | O95757.3 |
| UniProt Secondary Accession: | O95757,Q4W5M5, Q8IWA2, A2ICT2, |
| UniProt Related Accession: | O95757 |
| Molecular Weight: | 94,512 Da |
| NCBI Full Name: | Heat shock 70 kDa protein 4L |
| NCBI Synonym Full Names: | heat shock protein family A (Hsp70) member 4 like |
| NCBI Official Symbol: | HSPA4L |
| NCBI Official Synonym Symbols: | APG-1; HSPH3; Osp94 |
| NCBI Protein Information: | heat shock 70 kDa protein 4L |
| UniProt Protein Name: | Heat shock 70 kDa protein 4L |
| UniProt Synonym Protein Names: | Heat shock 70-related protein APG-1; Osmotic stress protein 94 |
| Protein Family: | Heat shock 70 kDa protein |
| UniProt Gene Name: | HSPA4L |
| UniProt Entry Name: | HS74L_HUMAN |
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