Anti-HSPA1L Antibody (MACO0016)

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SKU:
MACO0016
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Mouse
Isotype:
IgG
Applications:
ELISA
Applications:
WB
Applications:
IHC
Applications:
IF
Antibody Type:
Monoclonal Antibody
Conjugation:
Unconjugated

Description

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Product Name:Anti-HSPA1L Antibody
Product Sku:MACO0016
Size:50ug
Host Species:Mouse
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200
Species Reactivity:Human,Mouse,Rat
Immunogen:Synthetic Peptide
Form:Liquid
Storage Buffer:PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Clonality:Monoclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:
Synonyms:Heat shock 70 kDa protein 1-like/Heat shock 70 kDa protein 1A/1B
Product ImageWestern blot analysis of 1) Hela, 2) Mouse Brain, diluted at 1:2000.
Product ImageIF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100.
UniProt Protein Function:HSPA1L: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Not induced by heat shock. Expressed in spermatids. Belongs to the heat shock protein 70 family.
UniProt Protein Details:

Protein type:Heat shock protein; Mitochondrial; Chaperone

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: signalosome; nucleoplasm; mitochondrial matrix; cytosol

Molecular Function:protein binding; unfolded protein binding; ATP binding

Biological Process: binding of sperm to zona pellucida; protein refolding; response to unfolded protein

NCBI Summary:This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]
UniProt Code:P34931
NCBI GenInfo Identifier:23831140
NCBI Gene ID:3305
NCBI Accession:P34931.2
UniProt Secondary Accession:P34931,O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1, A6NNB0 B0UXW8,
UniProt Related Accession:P34931
Molecular Weight:641
NCBI Full Name:Heat shock 70 kDa protein 1-like
NCBI Synonym Full Names:heat shock 70kDa protein 1-like
NCBI Official Symbol:HSPA1L  
NCBI Official Synonym Symbols:HSP70T; hum70t; HSP70-1L; HSP70-HOM  
NCBI Protein Information:heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom
UniProt Protein Name:Heat shock 70 kDa protein 1-like
UniProt Synonym Protein Names:Heat shock 70 kDa protein 1-Hom; HSP70-Hom
Protein Family:Heat shock 70 kDa protein
UniProt Gene Name:HSPA1L  
UniProt Entry Name:HS71L_HUMAN
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