Cell Biology Antibodies 13

Anti-HS6ST1 Antibody (CAB17595)

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SKU:
CAB17595
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-HS6ST1 Antibody
Antibody SKU:CAB17595
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 302-411 of human HS6ST1 (NP_004798.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-251MG, U-87MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 302-411 of human HS6ST1 (NP_004798.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:YLFE RTFN LKFI RPFM QYNS TRAG GVEV DEDT IRRI EELN DLDM QLYD YAKD LFQQ RYQY KRQL ERRE QRLR SREE RLLH RAKE ALPR EDAD EPGR VPTE DYMS HIIE KW
Gene ID:9394
Uniprot:O60243
Cellular Location:
Calculated MW:
Observed MW:48kDa
Anti-HS6ST1 Antibody (CAB17595)Western blot - HS6ST1 Polyclonal Antibody (CAB17595)
Synonyms:HH15, HS6ST, HS6ST1
Background:The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Protein Function:6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.
NCBI Summary:The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O60243
NCBI GenInfo Identifier:148747866
NCBI Gene ID:9394
NCBI Accession:NP_004798.3
UniProt Related Accession:O60243
Molecular Weight:
NCBI Full Name:heparan-sulfate 6-O-sulfotransferase 1
NCBI Synonym Full Names:heparan sulfate 6-O-sulfotransferase 1
NCBI Official Symbol:HS6ST1  
NCBI Official Synonym Symbols:HH15; HS6ST  
NCBI Protein Information:heparan-sulfate 6-O-sulfotransferase 1
UniProt Protein Name:Heparan-sulfate 6-O-sulfotransferase 1
Protein Family:Heparan-sulfate 6-O-sulfotransferase
UniProt Gene Name:HS6ST1  
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