Cell Biology Antibodies 13
Anti-HS6ST1 Antibody (CAB17595)
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- SKU:
- CAB17595
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HS6ST1 Antibody |
| Antibody SKU: | CAB17595 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-411 of human HS6ST1 (NP_004798.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-251MG, U-87MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-411 of human HS6ST1 (NP_004798.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YLFE RTFN LKFI RPFM QYNS TRAG GVEV DEDT IRRI EELN DLDM QLYD YAKD LFQQ RYQY KRQL ERRE QRLR SREE RLLH RAKE ALPR EDAD EPGR VPTE DYMS HIIE KW |
| Gene ID: | 9394 |
| Uniprot: | O60243 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 48kDa |
 | Western blot - HS6ST1 Polyclonal Antibody (CAB17595) |
| Synonyms: | HH15, HS6ST, HS6ST1 |
| Background: | The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. |
| NCBI Summary: | The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60243 |
| NCBI GenInfo Identifier: | 148747866 |
| NCBI Gene ID: | 9394 |
| NCBI Accession: | NP_004798.3 |
| UniProt Related Accession: | O60243 |
| Molecular Weight: | |
| NCBI Full Name: | heparan-sulfate 6-O-sulfotransferase 1 |
| NCBI Synonym Full Names: | heparan sulfate 6-O-sulfotransferase 1 |
| NCBI Official Symbol: | HS6ST1 |
| NCBI Official Synonym Symbols: | HH15; HS6ST |
| NCBI Protein Information: | heparan-sulfate 6-O-sulfotransferase 1 |
| UniProt Protein Name: | Heparan-sulfate 6-O-sulfotransferase 1 |
| Protein Family: | Heparan-sulfate 6-O-sulfotransferase |
| UniProt Gene Name: | HS6ST1 |
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