Neuroscience

Anti-HPCAL4 Antibody (CAB15448)

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SKU:
CAB15448
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-HPCAL4 Antibody
Antibody SKU:CAB15448
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human HPCAL4 (NP_057341.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, 293T, LO2, Mouse brain, Mouse kidney, Mouse liver, Mouse testis, Rat brian
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human HPCAL4 (NP_057341.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGKT NSKL APEV LEDL VQNT EFSE QELK QWYK GFLK DCPS GILN LEEF QQLY IKFF PYGD ASKF AQHA FRTF DKNG DGTI DFRE FICA LSVT SRGS FEQK LNWA FEMY DLDG DGRI TRLE MLEI IEAI YKMV GTVI MMRM NQDG LTPQ QRVD KIFK KMDQ DKDD QITL EEFK EAAK SDPS IVLL LQCD MQK
Gene ID:51440
Uniprot:Q9UM19
Cellular Location:
Calculated MW:22kDa
Observed MW:22kDa
Synonyms:HPCAL4, HLP4
Background:The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:HPCAL4: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Belongs to the recoverin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: intracellular

Molecular Function:protein C-terminus binding; protein domain specific binding; protein binding; calcium channel regulator activity; calcium ion binding

Biological Process: central nervous system development; signal transduction

NCBI Summary:The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
UniProt Code:Q9UM19
NCBI GenInfo Identifier:51316542
NCBI Gene ID:51440
NCBI Accession:Q9UM19.3
UniProt Secondary Accession:Q9UM19,Q5TG97, Q8N611, B2R5U2, D3DPU1,
UniProt Related Accession:Q9UM19
Molecular Weight:
NCBI Full Name:Hippocalcin-like protein 4
NCBI Synonym Full Names:hippocalcin like 4
NCBI Official Symbol:HPCAL4  
NCBI Official Synonym Symbols:HLP4  
NCBI Protein Information:hippocalcin-like protein 4
UniProt Protein Name:Hippocalcin-like protein 4
Protein Family:Hippocalcin-like protein
UniProt Gene Name:HPCAL4  
UniProt Entry Name:HPCL4_HUMAN
Anti-HPCAL4 Antibody (CAB15448)Western blot analysis of extracts of various cell lines, using HPCAL4 antibody (CAB15448) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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