KO Validated Antibodies 2

Anti-HPCAL1 Antibody (CAB19964)[KO Validated]

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SKU:
CAB19964
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-HPCAL1 Antibody [KO Validated]
Antibody SKU:CAB19964
Antibody Size:20uL, 50uL, 100uL
Application:WB IP
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human HPCAL1.
Application:WB IP
Recommended Dilution:WB 1:500 - 1:2000 IP 1:20 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa
Immunogen:Recombinant protein of human HPCAL1.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3241
Uniprot:P37235
Cellular Location:Lipid-anchor, Membrane
Calculated MW:22kDa
Observed MW:18KDa
Anti-HPCAL1 Antibody [KO Validated] (CAB19964)Western blot analysis of extracts from normal (control) and HPCAL1 knockout (KO) HeLa cells, using HPCAL1 antibody (CAB19964) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:HPCAL1, BDR1, HLP2, VILIP-3
Background:The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniProt Protein Function:HPCAL1: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Belongs to the recoverin family.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 2p25.1

Molecular Function:protein binding

NCBI Summary:The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2012]
UniProt Code:P37235
NCBI GenInfo Identifier:20455519
NCBI Gene ID:3241
NCBI Accession:P37235.3
UniProt Secondary Accession:P37235,Q969S5,
UniProt Related Accession:P37235
Molecular Weight:22,313 Da
NCBI Full Name:Hippocalcin-like protein 1
NCBI Synonym Full Names:hippocalcin like 1
NCBI Official Symbol:HPCAL1  
NCBI Official Synonym Symbols:BDR1; HLP2; VILIP-3  
NCBI Protein Information:hippocalcin-like protein 1
UniProt Protein Name:Hippocalcin-like protein 1
UniProt Synonym Protein Names:Calcium-binding protein BDR-1; HLP2; Visinin-like protein 3; VILIP-3
Protein Family:Hippocalcin-like protein
UniProt Gene Name:HPCAL1  
UniProt Entry Name:HPCL1_HUMAN
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