Cell Biology Antibodies 14
Anti-HOXD8 Antibody (CAB16877)
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- SKU:
- CAB16877
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HOXD8 Antibody |
| Antibody SKU: | CAB16877 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human HOXD8 (NP_001186675.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SKOV3, Mouse ovary, Rat ovary |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human HOXD8 (NP_001186675.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RQTY SRFQ TLEL EKEF LFNP YLTR KRRI EVSH ALAL TERQ VKIW FQNR RMKW KKEN NKDK FPVS RQEV KDGE TKKE AQEL EEDR AEGL TN |
| Gene ID: | 3234 |
| Uniprot: | P13378 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 32kDa |
 | Western blot - HOXD8 Polyclonal Antibody (CAB16877) |
| Synonyms: | HOXD8, HOX4, HOX4E, HOX5.4 |
| Background: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | HOXD8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2q31.1 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
| UniProt Code: | P13378 |
| NCBI GenInfo Identifier: | 13124737 |
| NCBI Gene ID: | 3234 |
| NCBI Accession: | P13378.2 |
| UniProt Secondary Accession: | P13378,Q5BL00, Q8IXZ1, F8WBG7, |
| UniProt Related Accession: | P13378 |
| Molecular Weight: | 8,354 Da |
| NCBI Full Name: | Homeobox protein Hox-D8 |
| NCBI Synonym Full Names: | homeobox D8 |
| NCBI Official Symbol: | HOXD8 |
| NCBI Official Synonym Symbols: | HOX4; HOX4E; HOX5.4 |
| NCBI Protein Information: | homeobox protein Hox-D8 |
| UniProt Protein Name: | Homeobox protein Hox-D8 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-4E; Homeobox protein Hox-5.4 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXD8 |
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