Epigenetics & Nuclear Signaling Antibodies 2

Anti-HOXD3 Antibody (CAB15279)

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SKU:
CAB15279
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-HOXD3 Antibody
Antibody SKU:CAB15279
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Mouse spinal cord, Rat spinal cord, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ASQS PERS PPLG GAAG HVAY SGQL PPVP GLAY DAPS PPAF AKSQ PNMY GLAA YTAP LSSC LPQQ KRYA APEF EPHP MASN GGGF ASAN LQGS PVYV GGNF VESM APAS GPVF NLGH LSHP SSAS VDYS CAAQ IPGN HHHG PCDP HPTY TDLS AHHS SQGR LPEA PKLT HL
Gene ID:3232
Uniprot:P31249
Cellular Location:Nucleus
Calculated MW:45kDa
Observed MW:55kDa
Synonyms:HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1
Background:This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.
NCBI Summary:This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes. [provided by RefSeq, Jul 2008]
UniProt Code:P31249
NCBI GenInfo Identifier:19923391
NCBI Gene ID:3232
NCBI Accession:NP_008829
UniProt Related Accession:P31249
Molecular Weight:46kDa
NCBI Full Name:homeobox protein Hox-D3
NCBI Synonym Full Names:homeobox D3
NCBI Official Symbol:HOXD3  
NCBI Official Synonym Symbols:HOX4; HOX1D; HOX4A; Hox-4.1  
NCBI Protein Information:homeobox protein Hox-D3
UniProt Protein Name:Homeobox protein Hox-D3
UniProt Synonym Protein Names:Homeobox protein Hox-4A
UniProt Gene Name:HOXD3  
UniProt Entry Name:HXD3_HUMAN
Anti-HOXD3 Antibody (CAB15279)Western blot analysis of extracts of various cell lines, using HOXD3 antibody (CAB15279) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90S.
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