Name: Anti-HOXC4 Antibody (CAB8986)
Brand: Epigenetics & Nuclear Signaling Antibodies 4
SKU: CAB8986
Availability: OutOfStock

Antibody Name:	Anti-HOXC4 Antibody
Antibody SKU:	CAB8986
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HOXC4 (NP_055435.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	LO2, HeLa, Mouse kidney

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HOXC4 (NP_055435.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	PEHS PEYY GRTR ESGF QHHH QELY PPPP PRPS YPER QYSC TSLQ GPGN SRGH GPAQ AGHH HPEK SQSL CEPA PLSG ASAS PSPA PPAC SQPA PDHP SSAA S
Gene ID:	3221
Uniprot:	P09017
Cellular Location:	Nucleus
Calculated MW:	29kDa
Observed MW:	30kDa

Synonyms:

HOXC4, HOX3, HOX3E, cp19

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.

UniProt Protein Function:	HOXC4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily.
UniProt Protein Details:	Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: nucleus Molecular Function:protein binding
NCBI Summary:	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. [provided by RefSeq, Jul 2008]
UniProt Code:	P09017
NCBI GenInfo Identifier:	281185468
NCBI Gene ID:	3221
NCBI Accession:	P09017.2
UniProt Related Accession:	P09017
Molecular Weight:	29,811 Da
NCBI Full Name:	Homeobox protein Hox-C4
NCBI Synonym Full Names:	homeobox C4
NCBI Official Symbol:	HOXC4
NCBI Official Synonym Symbols:	HOX3; cp19; HOX3E
NCBI Protein Information:	homeobox protein Hox-C4
UniProt Protein Name:	Homeobox protein Hox-C4
UniProt Synonym Protein Names:	Homeobox protein CP19; Homeobox protein Hox-3E
Protein Family:	Homeobox protein
UniProt Gene Name:	HOXC4
UniProt Entry Name:	HXC4_HUMAN

Anti-HOXC4 Polyclonal Antibody (CAB8986)

Western blot analysis of extracts of various cell lines, using HOXC4 antibody (CAB8986) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 300s.

Antibodies

Anti-HOXC4 Antibody (CAB13856)

HOXC4 Antibody (PACO09778)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)