Epigenetics & Nuclear Signaling Antibodies 1

Anti-HOXB9 Antibody (CAB10222)

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SKU:
CAB10222
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-HOXB9 Antibody
Antibody SKU:CAB10222
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human HOXB9 (NP_076922.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human HOXB9 (NP_076922.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSIS GTLS SYYV DSII SHES EDAP PAKF PSGQ YASS RQPG HAEH LEFP SCSF QPKA PVFG ASWA PLSP HASG SLPS VYHP
Gene ID:3219
Uniprot:P17482
Cellular Location:Nucleus
Calculated MW:28kDa
Observed MW:28kDa
Synonyms:HOXB9, HOX-2.5, HOX2, HOX2E
Background:This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
UniProt Protein Function:HOXB9: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: mitochondrion; nucleoplasm

Molecular Function:protein binding

Biological Process: Wnt receptor signaling pathway through beta-catenin

NCBI Summary:This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]
UniProt Code:P17482
NCBI GenInfo Identifier:20141507
NCBI Gene ID:3219
NCBI Accession:P17482.2
UniProt Secondary Accession:P17482,Q9H1I1, B2RDB7,
UniProt Related Accession:P17482
Molecular Weight:28,059 Da
NCBI Full Name:Homeobox protein Hox-B9
NCBI Synonym Full Names:homeobox B9
NCBI Official Symbol:HOXB9  
NCBI Official Synonym Symbols:HOX2; HOX2E; HOX-2.5  
NCBI Protein Information:homeobox protein Hox-B9
UniProt Protein Name:Homeobox protein Hox-B9
UniProt Synonym Protein Names:Homeobox protein Hox-2.5; Homeobox protein Hox-2E
Protein Family:Homeobox protein
UniProt Gene Name:HOXB9  
UniProt Entry Name:HXB9_HUMAN
Anti-HOXB9 Antibody (CAB10222)Western blot analysis of extracts of mouse kidney, using HOXB9 antibody (CAB10222) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
Anti-HOXB9 Antibody (CAB10222)Immunofluorescence analysis of HeLa cells using HOXB9 antibody (CAB10222) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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