Epigenetics & Nuclear Signaling Antibodies 4

Anti-HOXB7 Antibody (CAB6925)

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SKU:
CAB6925
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-HOXB7 Antibody
Antibody SKU:CAB6925
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXB7 (NP_004493.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:Mouse kidney, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXB7 (NP_004493.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSSL YYAN TLFS KYPA SSSV FATG AFPE QTSC AFAS NPQR PGYG AGSG ASFA ASMQ GLYP GGGG MAGQ SAAG VYAA GYGL EPSS FNMH CAPF EQNL SGVC PGDS AKAA GAKE QRDS DLAA
Gene ID:3217
Uniprot:P09629
Cellular Location:Nucleus
Calculated MW:24kDa
Observed MW:24kDa
Synonyms:HOXB7, HHO.C1, HOX2, HOX2C, Hox-2.3
Background:This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
UniProt Protein Function:HOXB7: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.
UniProt Protein Details:

Protein type:DNA-binding; Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: cytosol; nuclear body; nucleoplasm

Molecular Function:protein binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter

NCBI Summary:This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
UniProt Code:P09629
NCBI GenInfo Identifier:311033482
NCBI Gene ID:3217
NCBI Accession:P09629.4
UniProt Secondary Accession:P09629,Q15957, Q53FN3, Q96BQ6, A8K3N8,
UniProt Related Accession:P09629
Molecular Weight:24,015 Da
NCBI Full Name:Homeobox protein Hox-B7
NCBI Synonym Full Names:homeobox B7
NCBI Official Symbol:HOXB7  
NCBI Official Synonym Symbols:HOX2; HOX2C; HHO.C1; Hox-2.3  
NCBI Protein Information:homeobox protein Hox-B7
UniProt Protein Name:Homeobox protein Hox-B7
UniProt Synonym Protein Names:Homeobox protein HHO.C1; Homeobox protein Hox-2C
Protein Family:Homeobox protein
UniProt Gene Name:HOXB7  
Anti-HOXB7 Antibody (CAB6925)Western blot analysis of extracts of various cell lines, using HOXB7 antibody (CAB6925) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 15s.
Anti-HOXB7 Antibody (CAB6925)Immunofluorescence analysis of U2OS cells using HOXB7 antibody (CAB6925).
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