Description
| Antibody Name: | Anti-HOXB7 Antibody |
| Antibody SKU: | CAB6925 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXB7 (NP_004493.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse kidney, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXB7 (NP_004493.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSSL YYAN TLFS KYPA SSSV FATG AFPE QTSC AFAS NPQR PGYG AGSG ASFA ASMQ GLYP GGGG MAGQ SAAG VYAA GYGL EPSS FNMH CAPF EQNL SGVC PGDS AKAA GAKE QRDS DLAA |
| Gene ID: | 3217 |
| Uniprot: | P09629 |
| Cellular Location: | Nucleus |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
| Synonyms: | HOXB7, HHO.C1, HOX2, HOX2C, Hox-2.3 |
| Background: | This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. |
| UniProt Protein Function: | HOXB7: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis; Transcription factor Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: cytosol; nuclear body; nucleoplasm Molecular Function:protein binding Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09629 |
| NCBI GenInfo Identifier: | 311033482 |
| NCBI Gene ID: | 3217 |
| NCBI Accession: | P09629.4 |
| UniProt Secondary Accession: | P09629,Q15957, Q53FN3, Q96BQ6, A8K3N8, |
| UniProt Related Accession: | P09629 |
| Molecular Weight: | 24,015 Da |
| NCBI Full Name: | Homeobox protein Hox-B7 |
| NCBI Synonym Full Names: | homeobox B7 |
| NCBI Official Symbol: | HOXB7 |
| NCBI Official Synonym Symbols: | HOX2; HOX2C; HHO.C1; Hox-2.3 |
| NCBI Protein Information: | homeobox protein Hox-B7 |
| UniProt Protein Name: | Homeobox protein Hox-B7 |
| UniProt Synonym Protein Names: | Homeobox protein HHO.C1; Homeobox protein Hox-2C |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXB7 |
 | Western blot analysis of extracts of various cell lines, using HOXB7 antibody (CAB6925) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 15s. |
 | Immunofluorescence analysis of U2OS cells using HOXB7 antibody (CAB6925). |
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