Epigenetics & Nuclear Signaling Antibodies 4
Anti-HOXA10 Antibody (CAB8550)
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- SKU:
- CAB8550
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-HOXA10 Antibody |
| Antibody SKU: | CAB8550 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 236-336 of human HOXA10 (NP_061824.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SKOV3, HT-29, Rat kidney, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 236-336 of human HOXA10 (NP_061824.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LGAG PFPA QPPG RGFD LPPA LASG SADA ARKE RALD SPPP PTLA CGSG GGSQ GDEE AHAS SSAA EELS PAPS ESSK ASPE KDSL GNSK GENA ANWL TAKS G |
| Gene ID: | 3206 |
| Uniprot: | P31260 |
| Cellular Location: | Nucleus |
| Calculated MW: | 11kDa/42kDa |
| Observed MW: | 53kDa |
| Synonyms: | HOXA10, HOX1, HOX1.8, HOX1H, PL |
| Background: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. |
| UniProt Protein Function: | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. |
| NCBI Summary: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | P31260 |
| NCBI GenInfo Identifier: | 182765442 |
| NCBI Gene ID: | 3206 |
| NCBI Accession: | NP_061824.3 |
| UniProt Secondary Accession: | P31260,O43370, O43605, Q15949, Q504T1, |
| UniProt Related Accession: | P31260 |
| Molecular Weight: | 45 |
| NCBI Full Name: | homeobox protein Hox-A10 |
| NCBI Synonym Full Names: | homeobox A10 |
| NCBI Official Symbol: | HOXA10 |
| NCBI Official Synonym Symbols: | PL; HOX1; HOX1H; HOX1.8 |
| NCBI Protein Information: | homeobox protein Hox-A10 |
| UniProt Protein Name: | Homeobox protein Hox-A10 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-1.8; Homeobox protein Hox-1H; PL |
| UniProt Gene Name: | HOXA10 |
 | Western blot analysis of extracts of various cell lines, using HOXA10 antibody (CAB8550) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Western blot analysis of extracts of Mouse kidney, using HOXA10 antibody (CAB8550) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. |
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