Anti-HLTF Antibody (CAB5068)
- SKU:
- CAB5068
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HIP116
- Synonyms:
- HIP116A
- Synonyms:
- HLTF1
- Synonyms:
- RNF80
- Synonyms:
- SMARCA3
- Synonyms:
- SNF2L3
- Synonyms:
- ZBU1
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | HLTF Rabbit mAb |
| Product Code: | CAB5068 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human HLTF |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, HepG2, Mouse lung, Mouse heart, Rat lung |
| Immunogen: | A synthesized peptide derived from human HLTF |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6596 |
| Uniprot: | Q14527 |
| Cellular Location: | Cytoplasm, Nucleus, nucleolus, nucleoplasm |
| Calculated MW: | 120kDa |
| Observed MW: | 114kDa |
| UniProt Protein Function: | SMARCA3: an enzyme with apparent ATP-dependent DNA helicase activity. Belongs to the SNF2/RAD54 helicase family, RAD16 subfamily. Two alternatively spliced human isoforms have been described. |
| UniProt Protein Details: | Protein type:Ligase; EC 3.6.1.-; Nucleolus; EC 3.6.4.-; EC 6.3.2.-; Ubiquitin conjugating system; Helicase; EC 6.3.2.19; DNA-binding; Ubiquitin ligase Chromosomal Location of Human Ortholog: 3q25.1-q26.1 Cellular Component: membrane; nucleoplasm; nucleus Molecular Function:DNA binding; protein binding; ubiquitin protein ligase binding Biological Process: regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14527 |
| NCBI GenInfo Identifier: | 60390864 |
| NCBI Gene ID: | 6596 |
| NCBI Accession: | Q14527.2 |
| UniProt Secondary Accession: | Q14527,Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9 D3DNH3, |
| UniProt Related Accession: | Q14527 |
| Molecular Weight: | 99,919 Da |
| NCBI Full Name: | Helicase-like transcription factor |
| NCBI Synonym Full Names: | helicase like transcription factor |
| NCBI Official Symbol: | HLTF |
| NCBI Official Synonym Symbols: | ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3 |
| NCBI Protein Information: | helicase-like transcription factor |
| UniProt Protein Name: | Helicase-like transcription factor |
| UniProt Synonym Protein Names: | DNA-binding protein/plasminogen activator inhibitor 1 regulator; HIP116; RING finger protein 80; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; Sucrose nonfermenting protein 2-like 3 |
| Protein Family: | Helicase-like transcription factor |
| UniProt Gene Name: | HLTF |
| UniProt Entry Name: | HLTF_HUMAN |
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