Anti-HJURP Antibody (CAB20169)

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SKU:
CAB20169
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
FAKTS
Synonyms:
URLC9
Synonyms:
hFLEG1

Description

Product Name:HJURP Rabbit pAb
Product Code:CAB20169
Size:50uL, 100uL
Synonyms:FAKTS, URLC9, hFLEG1
Applications:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human HJURP.
Applications:WB
Recommended Dilutions:WB 1:1000 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat thymus
Immunogen:Recombinant protein of human HJURP.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55355
Uniprot:Q8NCD3
Calculated MW:84kDa
Observed MW:80KDa
UniProt Protein Function:HJURP: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Histone-binding; NucleolusChromosomal Location of Human Ortholog: 2q37.1Cellular Component: chromosome, pericentric region; cytoplasm; nucleolus; nucleoplasm; nucleusMolecular Function: histone binding; identical protein binding; protein bindingBiological Process: chromosome segregation; DNA replication-independent nucleosome assembly at centromere; regulation of DNA binding; regulation of protein complex assembly
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8NCD3
NCBI GenInfo Identifier:239938642
NCBI Gene ID:55355
NCBI Accession:Q8NCD3.2
UniProt Secondary Accession:Q8NCD3,Q9BUT2, Q9NSL8, A8IRH5, B4DWR0, B4DZV4
UniProt Related Accession:Q8NCD3
Molecular Weight:74,372 Da
NCBI Full Name:Holliday junction recognition protein
NCBI Synonym Full Names:Holliday junction recognition protein
NCBI Official Symbol:HJURP  
NCBI Official Synonym Symbols:FAKTS; URLC9; hFLEG1  
NCBI Protein Information:Holliday junction recognition protein
UniProt Protein Name:Holliday junction recognition protein
UniProt Synonym Protein Names:14-3-3-associated AKT substrate; Fetal liver-expressing gene 1 protein; Up-regulated in lung cancer 9
Protein Family:Holliday junction recognition protein
UniProt Gene Name:HJURP  
UniProt Entry Name:HJURP_HUMAN
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