Anti-HJURP Antibody (CAB20169)
- SKU:
- CAB20169
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FAKTS
- Synonyms:
- URLC9
- Synonyms:
- hFLEG1
Description
| Product Name: | HJURP Rabbit pAb |
| Product Code: | CAB20169 |
| Size: | 50uL, 100uL |
| Synonyms: | FAKTS, URLC9, hFLEG1 |
| Applications: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human HJURP. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat thymus |
| Immunogen: | Recombinant protein of human HJURP. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55355 |
| Uniprot: | Q8NCD3 |
| Calculated MW: | 84kDa |
| Observed MW: | 80KDa |
| UniProt Protein Function: | HJURP: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Histone-binding; NucleolusChromosomal Location of Human Ortholog: 2q37.1Cellular Component: chromosome, pericentric region; cytoplasm; nucleolus; nucleoplasm; nucleusMolecular Function: histone binding; identical protein binding; protein bindingBiological Process: chromosome segregation; DNA replication-independent nucleosome assembly at centromere; regulation of DNA binding; regulation of protein complex assembly |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NCD3 |
| NCBI GenInfo Identifier: | 239938642 |
| NCBI Gene ID: | 55355 |
| NCBI Accession: | Q8NCD3.2 |
| UniProt Secondary Accession: | Q8NCD3,Q9BUT2, Q9NSL8, A8IRH5, B4DWR0, B4DZV4 |
| UniProt Related Accession: | Q8NCD3 |
| Molecular Weight: | 74,372 Da |
| NCBI Full Name: | Holliday junction recognition protein |
| NCBI Synonym Full Names: | Holliday junction recognition protein |
| NCBI Official Symbol: | HJURP |
| NCBI Official Synonym Symbols: | FAKTS; URLC9; hFLEG1 |
| NCBI Protein Information: | Holliday junction recognition protein |
| UniProt Protein Name: | Holliday junction recognition protein |
| UniProt Synonym Protein Names: | 14-3-3-associated AKT substrate; Fetal liver-expressing gene 1 protein; Up-regulated in lung cancer 9 |
| Protein Family: | Holliday junction recognition protein |
| UniProt Gene Name: | HJURP |
| UniProt Entry Name: | HJURP_HUMAN |
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