Anti-Hex Antibody (CAB19689)

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SKU:
CAB19689
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HEX
Synonyms:
HMPH
Synonyms:
HOX11L-PEN
Synonyms:
PRH
Synonyms:
PRHX

Description

Product Name:Hex Rabbit mAb
Product Code:CAB19689
Size:20uL, 50uL, 100uL
Synonyms:HEX, HMPH, HOX11L-PEN, PRH, PRHX
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Hex
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HepG2
Immunogen:A synthesized peptide derived from human Hex
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3087
Uniprot:Q03014
Calculated MW:30kDa
Observed MW:30KDa
UniProt Protein Function:HHEX: Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 10q23.33Cellular Component: cytoplasm; nucleusMolecular Function: DNA bending activity; eukaryotic initiation factor 4E binding; protein binding; protein homodimerization activity; sequence-specific DNA binding; TATA-binding protein binding; transcription factor bindingBiological Process: anterior/posterior pattern formation; B cell differentiation; cell differentiation; cell proliferation; mRNA export from nucleus; negative regulation of angiogenesis; negative regulation of cyclin-dependent protein kinase activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of vascular endothelial growth factor receptor signaling pathway; poly(A)+ mRNA export from nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of Wnt receptor signaling pathway
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]
UniProt Code:Q03014
NCBI GenInfo Identifier:547658
NCBI Gene ID:3087
NCBI Accession:Q03014.1
UniProt Secondary Accession:Q03014,Q96CE9, B1AQ17
UniProt Related Accession:Q03014
Molecular Weight:30,022 Da
NCBI Full Name:Hematopoietically-expressed homeobox protein HHEX
NCBI Synonym Full Names:hematopoietically expressed homeobox
NCBI Official Symbol:HHEX  
NCBI Official Synonym Symbols:HEX; PRH; HMPH; PRHX; HOX11L-PEN  
NCBI Protein Information:hematopoietically-expressed homeobox protein HHEX
UniProt Protein Name:Hematopoietically-expressed homeobox protein HHEX
UniProt Synonym Protein Names:Homeobox protein PRH
Protein Family:Hematopoietically-expressed homeobox protein
UniProt Gene Name:HHEX  
UniProt Entry Name:HHEX_HUMAN
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