Cell Biology Antibodies 14
Anti-HELZ Antibody (CAB17065)
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- SKU:
- CAB17065
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HELZ Antibody |
| Antibody SKU: | CAB17065 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human HELZ (NP_055692.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human HELZ (NP_055692.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEDR RAEK SCEQ ACES LKRQ DYEM ALKH CTEA LLSL GQYS MADF TGPC PLEI ERIK IESL LYRI ASFL QLKN YVQA DEDC RHVL GEGL AKGE DAFR AVLC CM |
| Gene ID: | 9931 |
| Uniprot: | P42694 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | HELZ, DHRC, DRHC, HUMORF5 |
| Background: | HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]). |
| UniProt Protein Function: | HELZ: May act as an helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo. Belongs to the DNA2/NAM7 helicase family. |
| UniProt Protein Details: | Protein type:EC 3.6.1.-; EC 3.6.4.-; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: membrane; nucleus Molecular Function:ATP binding; helicase activity; metal ion binding; protein binding; RNA binding |
| NCBI Summary: | HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P42694 |
| NCBI GenInfo Identifier: | 1519313142 |
| NCBI Gene ID: | 9931 |
| NCBI Accession: | NM_014877.4 |
| UniProt Related Accession: | P42694 |
| Molecular Weight: | |
| NCBI Full Name: | Homo sapiens helicase with zinc finger (HELZ), transcript variant 1, mRNA |
| NCBI Synonym Full Names: | helicase with zinc finger |
| NCBI Official Symbol: | HELZ |
| NCBI Official Synonym Symbols: | DHRC; DRHC; HUMORF5 |
| NCBI Protein Information: | probable helicase with zinc finger domain |
| UniProt Protein Name: | Probable helicase with zinc finger domain |
| UniProt Synonym Protein Names: | Down-regulated in human cancers protein |
| Protein Family: | Probable helicase with zinc finger domain |
| UniProt Gene Name: | HELZ |
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