Epigenetics & Nuclear Signaling Antibodies 1

Anti-HEL308 Antibody (CAB12661)

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SKU:
CAB12661
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-HEL308 Antibody
Antibody SKU:CAB12661
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HEL308 (NP_598375.2).
Application:WB IHC
Recommended Dilution:WB 1:1000 - 1:3000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, LO2, HeLa, Raji, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HEL308 (NP_598375.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDEC GSRI RRRV SLPK RNRP SLGC IFGA PTAA ELEP GDEG KEEE EMVA ENRR RKTA GVLP VEVQ PLLL SDSP ECLV LGGG DTNP DLLR HMPT DRGV GDQP NDSE VDMF GDYD SFTE NSFI AQVD DLEQ KYMQ LPEH KKHA TDFA TENL CSES IKNK LSIT TIGN LTEL QTDK HTEN QSGY EGVT IEPG ADLL YDVP SSQA IYFE NLQN SSND LGDH SMKE RDWK SSSH NTVN EELP HNCI EQPQ QNDE SSSK VRTS SDMN RRKS IKDH LK
Gene ID:113510
Uniprot:Q8TDG4
Cellular Location:
Calculated MW:15kDa/28kDa/35kDa/124kDa
Observed MW:124kDa
Synonyms:HELQ, HEL308
Background:
UniProt Protein Function:HEL308: DNA-dependent ATPase and 5' to 3' DNA helicase. Belongs to the helicase family. SKI2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.6.4.12; Helicase

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: nucleolus; nucleoplasm

Biological Process: double-strand break repair via homologous recombination

NCBI Summary:HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 [PubMed 11751861]).[supplied by OMIM, Mar 2008]
UniProt Code:Q8TDG4
NCBI GenInfo Identifier:296434521
NCBI Gene ID:113510
NCBI Accession:Q8TDG4.2
UniProt Secondary Accession:Q8TDG4,Q05DF9, Q502W9, Q659B8, Q6ZQX4, Q6ZTS4, Q96EX7
UniProt Related Accession:Q8TDG4
Molecular Weight:15,330 Da
NCBI Full Name:Helicase POLQ-like
NCBI Synonym Full Names:helicase, POLQ-like
NCBI Official Symbol:HELQ  
NCBI Official Synonym Symbols:HEL308  
NCBI Protein Information:helicase POLQ-like
UniProt Protein Name:Helicase POLQ-like
UniProt Synonym Protein Names:Mus308-like helicase; POLQ-like helicase
Protein Family:Helicase
UniProt Gene Name:HELQ  
Anti-HEL308 Antibody (CAB12661)Western blot analysis of extracts of various cell lines, using HELQ antibody (CAB12661) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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