Anti-HE4/WFDC2 Antibody (CAB3276)
- SKU:
- CAB3276
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EDDM4
- Synonyms:
- HE4
- Synonyms:
- WAP5
- Synonyms:
- dJ461P17.6
- Research Area:
- Cell Biology
Description
| Product Name: | HE4/WFDC2 Rabbit mAb |
| Product Code: | CAB3276 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | EDDM4, HE4, WAP5, dJ461P17.6 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human HE4/WFDC2 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, HT-29, SKOV3, Mouse liver, Mouse kidney |
| Immunogen: | A synthesized peptide derived from human HE4/WFDC2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10406 |
| Uniprot: | Q14508 |
| Cellular Location: | Secreted |
| Calculated MW: | 23kDa |
| Observed MW: | 22kDa |
| UniProt Protein Function: | WFDC2: a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: extracellular space Molecular Function:serine-type endopeptidase inhibitor activity; aspartic-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; cysteine protease inhibitor activity Biological Process: spermatogenesis; proteolysis |
| NCBI Summary: | This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14508 |
| NCBI GenInfo Identifier: | 20141958 |
| NCBI Gene ID: | 10406 |
| NCBI Accession: | Q14508.2 |
| UniProt Secondary Accession: | Q14508,Q6IB27, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1 A2A2A5, A2A2A6, A6PVD5, |
| UniProt Related Accession: | Q14508 |
| Molecular Weight: | 124 |
| NCBI Full Name: | WAP four-disulfide core domain protein 2 |
| NCBI Synonym Full Names: | WAP four-disulfide core domain 2 |
| NCBI Official Symbol: | WFDC2 |
| NCBI Official Synonym Symbols: | HE4; WAP5; EDDM4; dJ461P17.6 |
| NCBI Protein Information: | WAP four-disulfide core domain protein 2; epididymal protein 4; epididymal secretory protein E4; putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; major epididymis-specific protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core |
| UniProt Protein Name: | WAP four-disulfide core domain protein 2 |
| UniProt Synonym Protein Names: | Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5 |
| Protein Family: | WAP four-disulfide core domain protein |
| UniProt Gene Name: | WFDC2 |
| UniProt Entry Name: | WFDC2_HUMAN |
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