Metabolism Antibodies 2
Anti-HDC Antibody (CAB5465)
- SKU:
- CAB5465
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-HDC Antibody |
| Antibody SKU: | CAB5465 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 453-662 of human HDC (NP_002103.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | K-562, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 453-662 of human HDC (NP_002103.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QFTT RDDI LRDW NLIR DAAT LILS QHCT SQPS PRVG NLIS QIRG ARAW ACGT SLQS VSGA GDDP VQAR KIIK QPQR VGAG PMKR ENGL HLET LLDP VDDC FSEE APDA TKHK LSSF LFSY LSVQ TKKK TVRS LSCN SVPV SAQK PLPT EASV KNGG SSRV RIFS RFPE DMMM LKKS AFKK LIKF YSVP SFPE CSSQ CGLQ LPCC PLQA MV |
| Gene ID: | 3067 |
| Uniprot: | P19113 |
| Cellular Location: | |
| Calculated MW: | 70kDa/74kDa |
| Observed MW: | 85kDa |
| Synonyms: | HDC |
| Background: | This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion, inflamation, and smooth muscle tone. |
| UniProt Protein Function: | Catalyzes the biosynthesis of histamine from histidine. |
| NCBI Summary: | This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010] |
| UniProt Code: | P19113 |
| NCBI GenInfo Identifier: | 1352220 |
| NCBI Gene ID: | 3067 |
| NCBI Accession: | P19113.2 |
| UniProt Secondary Accession: | P19113,A1L4G0, B7ZM01, |
| UniProt Related Accession: | P19113 |
| Molecular Weight: | 70,059 Da |
| NCBI Full Name: | Histidine decarboxylase |
| NCBI Synonym Full Names: | histidine decarboxylase |
| NCBI Official Symbol: | HDC |
| NCBI Protein Information: | histidine decarboxylase |
| UniProt Protein Name: | Histidine decarboxylase |
| Protein Family: | Headcase protein |
| UniProt Gene Name: | HDC |
 | Western blot analysis of extracts of various cell lines, using HDC antibody (CAB5465) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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