Cell Biology Antibodies 18
Anti-HCAR3 Antibody (CAB18400)
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- SKU:
- CAB18400
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HCAR3 Antibody |
| Antibody SKU: | CAB18400 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human HCAR3. |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Rat pancreas |
| Immunogen: | Recombinant protein of human HCAR3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8843 |
| Uniprot: | P49019 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 44kDa |
 | Western blot - HCAR3 Rabbit pAb (CAB18400) |
| Synonyms: | GPR109B, HCA3, HM74, PUMAG, Puma-g, HCAR3 |
| Background: |
| UniProt Protein Function: | GPR109B: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cell junction; integral to plasma membrane; plasma membrane |
| UniProt Code: | P49019 |
| NCBI GenInfo Identifier: | 519668680 |
| NCBI Gene ID: | 8843 |
| NCBI Accession: | P49019.3 |
| UniProt Secondary Accession: | P49019,Q8NGE4, A8K4G5, B2R830, E9PI97, |
| UniProt Related Accession: | P49019 |
| Molecular Weight: | 44,478 Da |
| NCBI Full Name: | Hydroxycarboxylic acid receptor 3 |
| NCBI Synonym Full Names: | hydroxycarboxylic acid receptor 3 |
| NCBI Official Symbol: | HCAR3 |
| NCBI Official Synonym Symbols: | HCA3; HM74; PUMAG; Puma-g; GPR109B |
| NCBI Protein Information: | hydroxycarboxylic acid receptor 3 |
| UniProt Protein Name: | Hydroxycarboxylic acid receptor 3 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2 |
| Protein Family: | Hydroxycarboxylic acid receptor |
| UniProt Gene Name: | HCAR3 |
| UniProt Entry Name: | HCAR3_HUMAN |
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