Cell Cycle Antibodies 1
Anti-HAUS6 Antibody (CAB4797)
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- SKU:
- CAB4797
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HAUS6
- Synonyms:
- Dgt6
- Synonyms:
- FAM29A
- Research Area:
- Cell Cycle
Description
| Product Name: | HAUS6 Rabbit pAb |
| Product Code: | CAB4797 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | HAUS6, Dgt6, FAM29A |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 676-955 of human HAUS6 (NP_060115.3). |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse spleen, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 676-955 of human HAUS6 (NP_060115.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DEPP TQNQ SDLL NKKV ICKQ DLEC LAFT KLSE TSRM ETFS PAVG NRID VMGG SEEE FMKI LDHL EVSC NKPS TNKT MLWN SFQI SSGI SSKS FKDN DFGI LHET LPEE VGHL SFNS SSSS EANF KLEP NSPM HGGT LLED VVGG RQTT PESD FNLQ ALRS RYEA LKKS LSKK REES YLSN SQTP ERHK PELS PTPQ NVQT DDTL NFLD TCDL HTEH IKPS LRTS IGER KRSL SPLI KFSP VEQR LRTT IACS LGEL PNLK EEDI LNKS LDAK EPPS DLTR |
| Gene ID: | 54801 |
| Uniprot: | Q7Z4H7 |
| Cellular Location: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle |
| Calculated MW: | 69kDa/104kDa/108kDa |
| Observed MW: | 109kDa |
| UniProt Protein Function: | HAUS6: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. Belongs to the HAUS6 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 9p22.1 Cellular Component: nucleoplasm; microtubule; centrosome; cytoplasm; microtubule organizing center; spindle Biological Process: mitosis; cell division; centrosome organization and biogenesis; spindle assembly |
| NCBI Summary: | The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
| UniProt Code: | Q7Z4H7 |
| NCBI GenInfo Identifier: | 85700957 |
| NCBI Gene ID: | 54801 |
| NCBI Accession: | Q7Z4H7.2 |
| UniProt Secondary Accession: | Q7Z4H7,Q05CG1, Q14CB6, Q14CD9, Q2TA91, Q6IQ10, Q6NZX5 Q8IZQ4, Q96FN0, Q9H950, B3KPK4, B4DX82, |
| UniProt Related Accession: | Q7Z4H7 |
| Molecular Weight: | 955 |
| NCBI Full Name: | HAUS augmin-like complex subunit 6 |
| NCBI Synonym Full Names: | HAUS augmin-like complex, subunit 6 |
| NCBI Official Symbol: | HAUS6 |
| NCBI Official Synonym Symbols: | Dgt6; FAM29A |
| NCBI Protein Information: | HAUS augmin-like complex subunit 6; dim gamma-tubulin homolog; family with sequence similarity 29, member A |
| UniProt Protein Name: | HAUS augmin-like complex subunit 6 |
| Protein Family: | HAUS augmin-like complex |
| UniProt Gene Name: | HAUS6 |
| UniProt Entry Name: | HAUS6_HUMAN |
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