Cell Cycle Antibodies 1

Anti-HAUS1 Antibody (CAB17250)

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SKU:
CAB17250
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-HAUS1 Antibody
Antibody SKU:CAB17250
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 120-250 of human HAUS1 (NP_612452.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 120-250 of human HAUS1 (NP_612452.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NDLT SDLF RTKS KSEE IKIE LEKL EKNL TATL VLEK CLQE DVKK AELH LSTE RAKV DNRR QNMD FLKA KSEE FRFG IKAA EEQL SARG MDAS LSHQ SLVA LSEK LARL KQQT IPLK KKLE SYLD LMPN PSL
Gene ID:115106
Uniprot:Q96CS2
Cellular Location:
Calculated MW:32kDa
Observed MW:Refer to figures
Synonyms:HAUS1, CCDC5, HEI-C, HEIC, HsT1461
Background:HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
UniProt Protein Function:Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
NCBI Summary:HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
UniProt Code:Q96CS2
NCBI GenInfo Identifier:19923971
NCBI Gene ID:115106
NCBI Accession:NP_612452.1
UniProt Secondary Accession:Q96CS2,Q8N837, B2RDM7,
UniProt Related Accession:Q96CS2
Molecular Weight:22,744 Da
NCBI Full Name:HAUS augmin-like complex subunit 1
NCBI Synonym Full Names:HAUS augmin like complex subunit 1
NCBI Official Symbol:HAUS1  
NCBI Official Synonym Symbols:HEIC; CCDC5; HEI-C; HsT1461  
NCBI Protein Information:HAUS augmin-like complex subunit 1
UniProt Protein Name:HAUS augmin-like complex subunit 1
UniProt Synonym Protein Names:Coiled-coil domain-containing protein 5; Enhancer of invasion-cluster; HEI-C
Protein Family:HAUS augmin-like complex
UniProt Gene Name:HAUS1  
Anti-HAUS1 Antibody (CAB17250)Western blot analysis of extracts of various cell lines, using HAUS1 antibody (CAB17250) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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