Cell Biology Antibodies 5
Anti-HAO2 Antibody (CAB15159)
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- SKU:
- CAB15159
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HAO2 Antibody |
| Antibody SKU: | CAB15159 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human HAO2 (NP_057611.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human HAO2 (NP_057611.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSLV CLTD FQAH AREQ LSKS TRDF IEGG ADDS ITRD DNIA AFKR IRLR PRYL RDVS EVDT RTTI QGEE ISAP ICIA PTGF HCLV WPDG EMST ARAA QAAG ICYI TSTF ASCS LEDI VIAA PEGL RWFQ LYVH PDLQ LNKQ LIQR VESL GFKA LVIT LDTP VCGN RRHD IRNQ LRRN LTLT DLQS PKKG NAIP YFQM TPIS TSLC WNDL SWFQ SITR LPII LKGI LTKE DAEL AVKH NVQG IIVS NHGG RQLD EVLA SIDA LTEV VAAV KGKI EVYL DGGV RTGN DVLK ALAL GAKC IFLG RPIL WGLA CKGE HGVK EVLN ILTN EFHT SMAL TGCR SVAE INRN LVQF SRL |
| Gene ID: | 51179 |
| Uniprot: | Q9NYQ3 |
| Cellular Location: | Peroxisome |
| Calculated MW: | 38kDa/40kDa |
| Observed MW: | 38kDa |
| Synonyms: | HAO2, GIG16, HAOX2 |
| Background: | This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | HAO2: Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 1.1.3.15; Oxidoreductase Chromosomal Location of Human Ortholog: 1p12 Cellular Component: mitochondrion; peroxisome Molecular Function:FMN binding; receptor binding; (S)-2-hydroxy-acid oxidase activity Biological Process: mandelate metabolic process; fatty acid oxidation; protein homooligomerization |
| NCBI Summary: | This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9NYQ3 |
| NCBI GenInfo Identifier: | 54234014 |
| NCBI Gene ID: | 51179 |
| NCBI Accession: | NP_001005783.1 |
| UniProt Secondary Accession: | Q9NYQ3,Q2TU86, Q5QP00, Q9UJS6, |
| UniProt Related Accession: | Q9NYQ3 |
| Molecular Weight: | 54.7 kDa |
| NCBI Full Name: | hydroxyacid oxidase 2 |
| NCBI Synonym Full Names: | hydroxyacid oxidase 2 (long chain) |
| NCBI Official Symbol: | HAO2 |
| NCBI Official Synonym Symbols: | GIG16; HAOX2 |
| NCBI Protein Information: | hydroxyacid oxidase 2; glycolate oxidase; long-chain L-2-hydroxy acid oxidase; long chain alpha-hydroxy acid oxidase; cell growth-inhibiting gene 16 protein; (S)-2-hydroxy-acid oxidase, peroxisomal |
| UniProt Protein Name: | Hydroxyacid oxidase 2 |
| UniProt Synonym Protein Names: | (S)-2-hydroxy-acid oxidase, peroxisomal; Cell growth-inhibiting gene 16 protein; Long chain alpha-hydroxy acid oxidase; Long-chain L-2-hydroxy acid oxidase |
| Protein Family: | Hydroxyacid oxidase |
| UniProt Gene Name: | HAO2 |
| UniProt Entry Name: | HAOX2_HUMAN |
 | Western blot analysis of extracts of Mouse kidney, using HAO2 antibody (CAB15159) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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